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Pediatric Sedation in the Emergency Department: Trends from a Nationwide Population-based Study in Korea, 2007–2018

Lee JY, Choi SJ, Park JS, Lee JS, Ryu JM, Yum MS

Background: Pediatric sedation in the emergency department (ED) is widely performed in Korea; thus exploring the trends of its use is necessary. This study aimed to investigate the characteristics of...
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Safety of chloral hydrate sedation in dental practice for children: an overview

Song S, Han M, Kim J

Chloral hydrate is the oldest and most common sedative drug used in moderate sedation for pediatric dental patients. Hence, the purpose of this article is to review the safety and...
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Adverse Events and Risk Factors Associated with Chloral Hydrate Sedation for Brain Magnetic Resonance Imaging in the Neonatal Intensive Care Unit

Park BS, Yoo YM, Noh OK, Park MS, Lee JH

PURPOSE: This study investigated the incidence of adverse events (AEs) and risk factors associated with sedation using chloral hydrate (CH) for brain magnetic resonance imaging (MRI) in the neonatal intensive...
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Comparison of sedation outcome according to the dose of chloral hydrate in children requiring laceration repair

Seo BK, Kim A, Jung HM, Kim AJ, Han SB

PURPOSE: To compare the sedation outcome according to the dose of per os chloral hydrate in children who underwent laceration repair in the emergency department (ED). METHODS: This retrospective study was...
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Administration and Efficiency Comparison of Chloral Hydrate during Pediatric Sedation

Bae JA, Choi YH, Kim AJ, Lee SH

  • KMID: 2328234
  • J Korean Soc Clin Toxicol.
  • 2016 Jun;14(1):9-15.
PURPOSE: In most emergency department (ED), sedation is required before carrying out an invasive procedure on a pediatric patient. In the ED setting, it is essential to determine the optimal...
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Assessment of chloral hydrate-centered pediatric sedation performed by non-anesthesiologists

Kim YS, Lim BG, Kang SW, Lee SH, Lee W, Lee IO

BACKGROUND: We aimed to evaluate the efficacy and safety of chloral hydrate-based pediatric sedation conducted by non-anesthesiologists. METHODS: The design and setting of this study was a single-center retrospective study performed...
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The alternative of oral sedation for pediatric dental care

Kim J, Kim S, Lee DW, Ryu DS

  • KMID: 2310703
  • J Dent Anesth Pain Med.
  • 2015 Mar;15(1):1-4.
In pediatric dentistry, chloral hydrate is habitually selected for sedation of uncooperative children. Although chloral hydrate has been used for decades, various adverse effects are reported and necessity for new...
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Drug Rash With Eosinophilia and Systemic Symptoms Syndrome Induced by Chloral Hydrate in Early Childhood

Yoo SD, Kim SG, Kim SH, Kim HY

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, also known as drug-induced hypersensitivity syndrome (DIHS), is a rare, acute and severe life-threatening systemic disease. DRESS syndrome is characterized by...
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Optimal Initial Dose of Chloral Hydrate in Management of Pediatric Facial Laceration

Koo SH, Lee DG, Shin H

BACKGROUND: Chloral hydrate (CH) is the primary agent most commonly used for pediatric sedation prior to diagnostic, therapeutic procedures. In the management of pediatric facial laceration, the initial dose of...
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Sedative Effect of Chlorpheniramine in Children Failed to sedate with Chloral hydrate and Midazolam

Kim HN, Yoon BG, Bae SY, Son YJ, Kim YO, Woo YJ

  • KMID: 2329622
  • J Korean Child Neurol Soc.
  • 2013 Mar;21(1):19-27.
PURPOSE: To evaluate the sedative effect of add-on chlorpheniramine in children with neurologic diseases failed to sedate with chloral hydrate and midazolam. METHODS: Thirty three patients who had not been successfully...
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Adverse Effects of Chloral Hydrate in Neonates: Frequency and Related Factors

Lee J, Youn YA, Kim SJ, Lee HS, Kim SY, Sung IK, Chun CS

PURPOSE: Chloral hydrate is a common drug frequently used for procedural sedation. But data on chloral hydrate use in the newborns are limited. This study examined the frequency of adverse...
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Airway Obstruction and Respiratory Distress Owing to Sedation by use of Chloral Hydrate & Ketamine Before Extraction of the Mesiodens in Patient with Bronchial Asthma & Tonsillar Hyperplasia: A Case Report

Choi YS, Kang SH, Kim MK, Lee CU, Yoo JH

The causes for airway obstruction include foreign body aspiration, congenital structural abnormalities of the airway, infection, etc. And the potential causes of acute respiratory distress contain many situations, like hyperventilation,...
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Sedative Effect of Sublingual Midazolam after Oral Chloral Hydrate or Hydroxyzine in Children

Lee H, Baek K, Jung S

Recently combining regimen of minimal doses of chloral hydrate, hydroxyzine and midazolam is good in sedation of children. Midazoalm, water soluble benzdiazepine, has rapid onset and relatively short duration of...
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Effect of Chloral Hydrate Used for Pediatric Sedation

Choi YS, Son YJ, Song ES, Cho YK, Kim YO, Kim CJ, Woo YJ

  • KMID: 2059408
  • J Korean Child Neurol Soc.
  • 2008 May;16(1):78-85.
PURPOSE: Sedation is often needed to perform an imaging study or procedure on a child. Although chloral hydrate is the most commonly used drug for pediatric sedation, little data are...
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The Comparison of Behavioral Response of Additional Submucosal Midazolam with Oral Chloral Hydrate, Hydroxyzine and Nitrous Oxide for Pediatric Conscious Sedation

Park H, Baek K, Jung S

No abstract available in English.
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Safety and Efficacy of Submucosal Midazolam When Combined with Oral Chloral Hydrate, Hydroxyzine and Nitrous Oxide Sedation by using Houpt's Scale

Park M, Kim Y, Jung S, Beak K

BACKGROUND: The purpose of this study was to compare the clinical safety and effect with and without additional submucosal midazolam to oral chloral hydrate and hydroxyzine when used for pediatric...
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Effect of Submucosal Midazolam on Percutaneous Saturation Percentage of Oxygen (SpOâ‚‚), End-tidal Carbon Dioxide (EtCOâ‚‚) and Physiologic Response When Combined with Chloral Hydrate, Hydroxyzine and Nitrous Oxide Sedation

Yu J, Kim Y, Jung S, Baek K

BACKGROUND: The aim of this study was to examine the difference of SpOâ‚‚, PR, EtCOâ‚‚, RR with submucosal injection of midazolam to oral chloral hydrate and hydroxyzine for pediatric patients METHODS:...
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The Comparison of Sedative Efficacy and Safety of Oral Chloral Hydrate and Intramuscular Ketamine in Children for Primary Repair in Emergency Department

Min JH, Do HS, Hong SW, Jeong WJ, Lee WS, Yi HY, Ryu S, Kim SW, Chung SP, Yoo IS

  • KMID: 2331494
  • J Korean Soc Emerg Med.
  • 2006 Dec;17(6):623-629.
PURPOSE: To compare the sedation quality of oral chloral hydrate against intramuscular ketamine in children requiring primary repair in the emergency department. METHODS: Patients needing primary repair of lacerations (range 1.6...
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The Sedative Effects of Submucosal Midazolam in Children

Lee YE, Park MK, Kim YH, Jung SH, Baek KW

PURPOSE: This retrospective study assessed the effectiveness of submucosal (SM) midazolam (M), oral chloral hydrate (CH), hydroxyzine (H), and nitrous oxide (N) 99 uncooperative pediatric dental patients over 182 sedation...
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A Case of Ventricular Tachycardia after Chloral Hydrate Ingestion

Lee HK, Jeong YS

  • KMID: 1967599
  • J Korean Pediatr Soc.
  • 2000 Oct;43(10):1390-1394.
Chloral hydrate is widely used as a sedative or hypnotic, especially in pediatric patients, but cardiac arrhythmia following chloral hydrate administration has rarely been reported in literature up to date. The most...
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