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Trends in Bloodstream Infections and Antimicrobial Susceptibilities at a University Hospital in Korea Between 2007 and 2016

Lim S, Yeom JS, Joo EJ, Cheong HS, Lee K, Woo HY, Park H, Kwon MJ

BACKGROUND: Blood culture is an important method for identifying infectious microorganisms and confirming that a selected antimicrobial treatment is appropriate. In this study, we investigated the annual changes in the...
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RNA-Seq for Gene Expression Profiling of Human Necrotizing Enterocolitis: a Pilot Study

Jung K, Koh I, Kim JH, Cheong HS, Park T, Nam SH, Jung SM, Sio CA, Kim SY, Jung E, Lee B, Kim HR, Shin E, Jung SE, Choi CW, Kim BI, Jung E, Shin HD

Necrotizing enterocolitis (NEC) characterized by inflammatory intestinal necrosis is a major cause of mortality and morbidity in newborns. Deep RNA sequencing (RNA-Seq) has recently emerged as a powerful technology enabling...
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Erratum: Vaccination guideline for Immigrant in Korea by Korean Society of Infectious Diseases

Yeom JS, Kwon KT, Lee J, Seo YB, Cheong HS, Kwon HH, Cheong HJ, The Committee of Adult Immunization, The Korean Society of Infectious Diseases

We found an error in our published article. Author name should be corrected.
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Vaccination guideline for Immigrant in Korea by Korean Society of Infectious Diseases

Yeom JS, Kwon KT, Lee J, Suh YB, Cheong HS, Kwon HH, Cheong HJ, The Committee of Adult Immunization, The Korean Society of Infectious Diseases

No abstract available.
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The association of 5-alpha reductase type 2 (SRD5A2) gene polymorphisms with prostate cancer in a Korean population

Choi SY, Kim HJ, Cheong HS, Myung SC

PURPOSE: Steroid 5-alpha reductase type 2 (SRD5A2) modifies testosterone to dihydrotestosterone (DHT) in the prostate. Single-nucleotide polymorphisms (SNPs) of the SRD5A2 gene might affect DHT. We sought to understand the...
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Association Analysis of TEC Polymorphisms with Aspirin-Exacerbated Respiratory Disease in a Korean Population

Lee JS, Bae JS, Park BL, Cheong HS, Kim JH, Kim JY, Namgoong S, Kim JO, Park CS, Shin HD

The tyrosine-protein kinase Tec (TEC) is a member of non-receptor tyrosine kinases and has critical roles in cell signaling transmission, calcium mobilization, gene expression, and transformation. TEC is also involved...
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Comprehensive Variant Screening of the UGT Gene Family

Kim JY, Cheong HS, Park BL, Kim LH, Namgoong S, Kim JO, Kim HD, Kim YH, Chung MW, Han SY, Shin HD

PURPOSE: UGT1A1, UGT2B7, and UGT2B15 are well-known pharmacogenes that belong to the uridine diphosphate glucuronyltransferase gene family. For personalized drug treatment, it is important to study differences in the frequency...
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Mortality of Community-Acquired Pneumonia in Korea: Assessed with the Pneumonia Severity Index and the CURB-65 Score

Kim HI, Kim SW, Chang HH, Cha SI, Lee JH, Ki HK, Cheong HS, Yoo KH, Ryu SY, Kwon KT, Lee BK, Choo EJ, Kim DJ, Kang CI, Chung DR, Peck KR, Song JH, Suh GY, Shim TS, Kim YK, Kim HY, Moon CS, Lee HK, Park SY, Oh JY, Jung SI, Park KH, Yun NR, Yoon SH, Sohn KM, Kim YS, Jung KS

The pneumonia severity index (PSI) and CURB-65 are widely used tools for the prediction of community-acquired pneumonia (CAP). This study was conducted to evaluate validation of severity scoring system including...
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Screening of Dihydropyrimidine Dehydrogenase Genetic Variants by Direct Sequencing in Different Ethnic Groups

Shin JG, Cheong HS, Kim JY, Kim LH, Han CS, Kim JO, Kim HD, Kim YH, Chung MW, Han SY, Shin HD

Dihydropyrimidine dehydrogenase (DPYD) is an enzyme that regulates the rate-limiting step in pyrimidine metabolism, especially catabolism of fluorouracil, a chemotherapeutic agent for cancer. In order to determine the genetic distribution...
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Screening of Genetic Polymorphisms of CYP3A4 and CYP3A5 Genes

Lee JS, Cheong HS, Kim LH, Kim JO, Seo DW, Kim YH, Chung MW, Han SY, Shin HD

Given the CYP3A4 and CYP3A5's impact on the efficacy of drugs, the genetic backgrounds of individuals and populations are regarded as an important factor to be considered in the prescription...
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WDR46 is a Genetic Risk Factor for Aspirin-Exacerbated Respiratory Disease in a Korean Population

Pasaje CF, Bae JS, Park BL, Cheong HS, Kim JH, Uh ST, Park CS, Shin HD

PURPOSE: The human WD repeat-containing protein 46 (WDR46; also known as C6orf11), located at the disease-relevant centromere side of the class II major histocompatibility complex region, is hypothesized to be...
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Potential Association of DCBLD2 Polymorphisms with Fall Rates of FEV1 by Aspirin Provocation in Korean Asthmatics

Park TJ, Kim JH, Park BL, Cheong HS, Bae JS, Pasaje CF, Park JS, Uh ST, Kim MK, Choi IS, Park CS, Shin HD

Aspirin exacerbated respiratory disease (AERD) is a clinical syndrome characterized by chronic rhinosinusitis with nasal polyposis and aspirin hypersensitivity. The aspirin-induced bronchospasm is mediated by mast cell and eosinophilic inflammation....
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Hypoglycemic Seizures Associated with Pentamidine for Pneumocystis jiroveci Pneumonia in a HIV Patient

Choi HS, Ki HK, Song KH, Cheong HS, Seo JW, Chung HA, Hwang Y

  • KMID: 2263421
  • Korean J Med.
  • 2012 Nov;83(5):679-682.
Trimethoprim-sulfamethoxazole (TMX-SMZ) is the initial treatment for Pneumocystis jiroveci pneumonia in human immunodeficiency virus (HIV) patients. About 20% of patients do not complete the TMX-SMZ treatment due to treatment failure...
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Spinal Cord Injury Incurred by Neck Massage

Cheong HS, Hong BY, Ko YA, Lim SH, Kim JS

  • KMID: 2391535
  • Ann Rehabil Med.
  • 2012 Oct;36(5):708-712.
Massage is generally accepted as a safe and a widely used modality for various conditions, such as pain, lymphedema, and facial palsy. However, several complications, some with devastating results, have...
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Survey of Elementary School Students and Their Mothers Awareness and Intake Patterns of Kimchi in Changwon

Cho AR, Kang OJ, Cheong HS

  • KMID: 2332339
  • J Korean Diet Assoc.
  • 2011 Aug;17(3):276-286.
This study aimed to examine consumers' interest, preference, and consumption frequency of Kimchi in elementary school students in the fifth grade and their mothers living in Changwon city. In a...
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An Adult Case of Chronic Active Epstein-Barr Virus Infection with Interstitial Pneumonitis

Joo EJ, Ha YE, Jung DS, Cheong HS, Wi YM, Song JH, Peck KR

Chronic active Epstein-Barr virus (CAEBV) infection is characterized by persistent infectious mononucleosis-like symptoms, an unusual pattern of Epstein-Barr virus (EBV) antibodies, detection of the EBV genome in affected tissues or...
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Polymorphisms of the Reg1alpha Gene and Early Onset Type 2 Diabetes in the Korean Population

Koo BK, Cho YM, Kimm K, Lee JY, Oh B, Park BL, Cheong HS, Shin HD, Ko KS, Park SG, Lee HK, Park KS

BACKGROUND: The Reg gene has been reported to be expressed in regenerating islets and Reg1 protein to be up-regulated at an early stage of diabetes in mice. As human Reg1alpha...
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Putative Association of ITGB1 Haplotype with the Clearance of HBV Infection

Park TJ, Chun JY, Bae JS, Kim JY, Lee JS, Pasaje CF, Park BL, Cheong HS, Lee HS, Kim YJ, Shin HD

  • KMID: 2166472
  • Genomics Inform.
  • 2010 Mar;8(1):9-18.
Integrins are transmembrane receptor proteins that mediate cell-cell adhesion and cell-extracellular matrix (ECM) adhesion. The deregulation of cell-ECM adhesion and the abnormal expression of beta1 (beta1) integrins (ITGB1s) are involved...
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Association Analysis of SERPINB5 Polymorphisms with HBV Clearance and HCC Occurrence in a Korean Population

Kim JY, Park TJ, Lee JS, Chun JY, Bae JS, Park BL, Cheong HS, Lee HS, Kim YJ, Shin HD

  • KMID: 2166471
  • Genomics Inform.
  • 2010 Mar;8(1):1-8.
Serpin peptidase inhibitor, Clade B (ovalbumin), Member 5 (SERPINB5), also known as maspin, is a potent tumor suppressor gene. It has correlations with many tumor cells, from pancreas cancer to...
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Prevalence of Extended-spectrum beta-lactamase among Enterobacteriacae Blood Isolates with Inducible AmpC beta-lactamase

Cheong HS, Ko KS, Kang CI, Chung DR, Peck KR, Song JH

BACKGROUND: Among the inducible AmpC beta-lactamase-producing members of the family Enterobacteriaceae such as Enterobacter spp., Citrobacter spp., Serratia spp., and Morganella morganii (ECSM), the prevalence of ESBL-producing isolates are increasing....
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