- Effects of a combination of chenodeoxycholic acid and ursodeoxycholic acid for gallstone dissolution
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Shin W
- KMID: 2143803
- Korean J Gastroenterol.
- 1992 Dec;24(6):1383-1390.
No abstract available. -
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- A Case of Cerebrotendinous Xanthomatosis
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Park CI, Kim YC, Shin JC, Kim YW, Lim KB
- KMID: 2323089
- J Korean Acad Rehabil Med.
- 1998 Apr;22(2):460-464.
Cerebrotendinous Xanthomatosis is a rare inherited autosomal recessive disorder characterized by an increased plasma cholestanol level and the accumulation of sterol in tendon and nervous system. The primary biochemical abnormality... -
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- Synthetic Bile Acid Derivative HS-1200-induced Apoptosis of Human Osteosarcoma Cells
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Kim GC, Her YS, Park JH, Moon YS, Yoo YH, Shin SH, Park BS
- KMID: 2092841
- Korean J Anat.
- 2004 Oct;37(5):449-457.
Bile acids and synthetic its derivatives induced apoptosis in various kinds of cancer cells and had anticancer effects. However, it wasn`t discovered those materials have apoptosis induced effects on osteosarcoma... -
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- The Analysis of Gallbladder Bile Acid Concentration in Patients with Colorectal Cancer
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Cho YJ, Hahm JS, Choi HS, Lee YW, Jeon YC, Sohn JH, Yoon BC, Lee MH, Lee DH, Kee CS, Park KN, Park YS, Jun KY
- KMID: 1571064
- Korean J Gastroenterol.
- 2000 Feb;35(2):233-241.
BACKGROUND/AIMS: Changes of bile acid concentration may play an important role in the carcinogenesis of colorectal cancer. We intended to assess the difference in bile acid concentrations between patients with... -
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- Synthetic Chenodeoxycholic Acid Derivative HS-1200-induced Apoptosis of Human Melanoma Cells
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Baek CJ, Min JH, Moon SH, Kim IR, Lee SE, Kim DH, Kim GC, Kwak HH, Park BS
- KMID: 1521309
- Korean J Phys Anthropol.
- 2007 Dec;20(4):363-373.
Bile acids and their synthetic derivatives induced apoptosis in various kinds of cancer cells and anticancer effects. It has been reported that the synthetic chenodeoxycholic acid (CDCA) derivatives showed apoptosis-inducing... -
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- Two Siblings with Cerebrotendinous Xanthomatosis
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Park JY, Shin DH, Choi JS, Park MY
- KMID: 2388398
- Korean J Dermatol.
- 2013 Jun;51(6):450-454.
Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive lipid storage disease caused by sterol 27-hydroxylase (CYP27) deficiency. We report two CTX siblings that were presented with typical manifestations such as... -
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- The relationship of bacterial and Helicobacter infection to composition of bile acid in biliary tract diseases
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Lee BS, Roe IH, Nam SW, Yoo K, Park HJ, Kim JW, Shin JH, Lee JH
- KMID: 2253145
- Korean J Med.
- 2001 Mar;60(3):215-221.
BACKGROUND: Bacterial and Helicobacter gene were commonly detected in diseased human bile, although the meaning of the presence of Helicobacter in biliary tract is still unclear. The aim of this... -
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- Synthetic CDCA Derivatives-Induced Apoptosis of Stomach Cancer Cell Line SNU-1 Cells
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Moon B, Kim MC, Park JS
- KMID: 2127913
- Cancer Res Treat.
- 2004 Apr;36(2):132-139.
PURPOSE: This study was conducted to explore whether CDCA derivatives induce apoptosis in a stomach cancer cell line, and to dissect the detailed mechanism underlying apoptosis. MATERIALS AND METHODS: The... -
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- A Case of Cri du Chat Syndrome with Developmental Delay Misdiagnosed as Fetal Alcohol Syndrome
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No SJ, Kim DO, Lee SM, Lee JS
- KMID: 2043931
- J Korean Child Neurol Soc.
- 2012 Mar;20(1):23-27.
Cri du Chat syndrome (CdCS) is a chromosomal disease resulting from a deletion on the short arm of chromosome 5. Characteristic features include high pitched cat-like cry, distinguishing facial features,... -
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- A Synthetic Chenodeoxycholic Acid Derivative, HS-1200-induced Apoptosis of RBL-2H3 Cells
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Koo BC, Kim JS, Kwak HH, Kim IR, Lee SE, Kim GC, Suh H, Park BS
- KMID: 1472504
- Korean J Anat.
- 2009 Mar;42(1):19-30.
Bile acids and synthetic bile acid derivatives induced apoptosis in various kinds of cancer cells and anticancer effects. Although synthetic chenodeoxycholic acid (CDCA) derivatives have been demonstrated to induce apoptosis... -
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- HS-1200 Overcomes the Resistance Conferred by Bcl-2 in Human Leukemic U937 Cells
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Park JY, Moon JB, Kim IR, Kim GC, Park BS, Kwak HH
- KMID: 1436476
- Int J Oral Biol.
- 2012 Sep;37(3):91-102.
Bcl-2 protects tumor cells from the apoptotic effects of various anti-neoplastic agents. Increased expression of Bcl-2 has been associated with a poor response to chemotherapy in various malignancies, including leukemia.... -
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- Apoptotic Effect of Co-Treatment with a Natural Product, Chios Gum Mastic, and a Synthetic Chenodeoxycholic Acid Derivative, HS-1200, on Human Osteosarcoma Cells
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Min JH, Kim MJ, Kim IR, Lee SE, Kwak HH, Kim GC, Park HR, Shin SH, Kim CH, Jeong NY, Suh H, Park BS
- KMID: 2283423
- Korean J Phys Anthropol.
- 2008 Jun;21(2):167-180.
Chios gum mastic (CGM) is a resinous exudate obtained from the stem and the main leaves of Pistacia lenticulus tree native to Mediterranean areas. Recently it reported that CGM induced... -
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- Efficacy of Magnesium Trihydrate of Ursodeoxycholic Acid and Chenodeoxycholic Acid for Gallstone Dissolution: A Prospective Multicenter Trial
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Hyun JJ, Lee HS, Kim CD, Dong SH, Lee SO, Ryu JK, Lee DH, Jeong S, Kim TN, Lee J, Koh DH, Park ET, Lee I, Yoo BM, Kim JH
- KMID: 2160640
- Gut Liver.
- 2015 Jul;9(4):547-555.
- doi: 10.5009/gnl15015
BACKGROUND/AIMS: Cholecystectomy is necessary for the treatment of symptomatic or complicated gallbladder (GB) stones, but oral litholysis with bile acids is an attractive alternative therapeutic option for asymptomatic or mildly... -
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- Toxicity of Bile Acids on Colon Cancer Cell Lines
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Park DK, Shin JH, Jun HJ, Kim KJ, Lee CY
- KMID: 2175280
- J Korean Cancer Assoc.
- 1999 Feb;31(1):126-133.
PURPOSE: Cytotoxicity of the bile acids on colon cancer cell lines was studied to know which bile acid was most cytotoxic to colonic mucosal epithelium. We performed agarose gel electrophoresis... -
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- A Novel Chenodeoxycholic Derivative HS-1200 Enhances Radiation-induced Apoptosis in Human MCF-7 Breast Cancer Cells
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Lee HS, Choi YM, Kwon HC, Song YS
- KMID: 2323832
- J Korean Soc Ther Radiol Oncol.
- 2004 Jun;22(2):145-154.
PURPOSE: To examine whether a synthetic bile acid derivatives (HS-1200) sensitizes the radiation-induced apoptosis in human breast cancer cells (MCF-7) and to investigate the underlying mechanism. MATERIALS AND MEHTODS: Human... -
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- Modulation of Apoptosis and Cell Cycle by Synthetic Bile Acid Derivatives
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Park SE, Im EO, Choi YH, Kim ND, Yoo YH
- KMID: 2092912
- Korean J Anat.
- 2008 Mar;41(1):1-11.
This paper outlines the current understanding of cell cycle modulation and induction of apoptosis in cancer cells by natural and synthetic bile acid. Bile acid homeostasis is tightly regulated in... -
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- Gastric Stump Cancer
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Oh YS, Kim YS, Sin YM, Lee SH, Moon YC, Choi KH, Chung BC
- KMID: 2372685
- J Korean Gastric Cancer Assoc.
- 2001 Sep;1(3):144-149.
PURPOSE: Gastric stump cancer is defined as a cancer that develops in the stomach after a resection in cases of non-malignant or malignant gastric disease. The interval between the gastrectomy... -
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- The Role of HS-1200 Induced Autophagy in Oral Cancer Cells
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Jang NM, Oh SH, Kim IR, Park HR, Park BS
- KMID: 2170779
- Int J Oral Biol.
- 2013 Sep;38(3):93-100.
Bile acids and synthetic bile acid derivatives induce apoptosis in various kinds of cancer cells and thus have anticancer properties. Recently, it has been suggested that autophagy may play an... -
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- Non-alcoholic fatty liver diseases: update on the challenge of diagnosis and treatment
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Oh H, Jun DW, Saeed WK, Nguyen MH
- KMID: 2373132
- Clin Mol Hepatol.
- 2016 Sep;22(3):327-335.
- doi: 10.3350/cmh.2016.0049
The prevalence of non-alcoholic fatty liver disease (NAFLD) is estimated to be 25-30% of the population, and is the most common cause of elevated liver enzymes in Korea. NAFLD is... -
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- Apoptotic Effect of Co-treatment with Chios Gum Mastic and HS-1200 on G361 Human Melanoma Cell Line
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Hur YJ, Kim YK, Kwak HH, Kim GC, Lee SE, Kim IR, Kim CH, Park BS
- KMID: 2092955
- Korean J Anat.
- 2009 Jun;42(2):83-92.
Chios gum mastic (CGM) is a resinous exudate obtained from the stem and the main leaves of Pistacia lenticulus tree native to Mediterranean areas. Recently it reported that CGM induce... -
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