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Juvenile Patient with LEOPARD Syndrome: Clinical Profile of a Genetically Confirmed Case

Wan P, Cheng Y, Chen Z, Chen J

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Evaluation of the Potential Association between NOS Gene Polymorphisms (iNOS G-954C and eNOS G894T) and Psoriasis

Duan X, Cheng Y, Gao L, Li L, Wang T, Zhang M

No abstract available.
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Characterization of Extended-Spectrum β-Lactamase Genes of Shigella flexneri Isolates With Fosfomycin Resistance From Patients in China

Liu Y, Cheng Y, Yang H, Hu L, Cheng J, Ye Y, Li J

BACKGROUND: The emergence of fosfomycin resistance and extended-spectrum β-lactamase (ESBL) genes is a serious threat to public health and a new challenge in shigellosis treatment. The purpose of this study...
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Novel Mutations in the UNC13D Gene Carried by a Chinese Neonate with Hemophagocytic Lymphohistiocytosis

Chen Y, Wang Z, Cheng Y, Tang Y

Hemophagocytic lymphohistiocytosis (HLH) in different ethnicities has been described in the literature, but few cases in patients of Chinese descent have been reported. Here, we describe the case of a...
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Identification and Genotypic Characterization of Potentially Pathogenic Acanthamoeba Isolated from Tap Water in Wuxi, China

Wang M, Sun G, Sun Y, You X, Li X, Cheng Y, Xuan Y

Members of genus Acanthamoeba are widely distributed in the environment. Some are pathogenic and cause keratitis and fatal granulomatous amoebic encephalitis. In this study, we isolated an Acanthamoeba CJW/W1 strain...
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Multiparametric Magnetic Resonance Imaging Characteristics of Prostate Tuberculosis

Cheng Y, Huang L, Zhang X, Ji Q, Shen W

OBJECTIVE: To describe the multiparametric magnetic resonance imaging (MRI) appearance of prostate tuberculosis. MATERIALS AND METHODS: Six patients with prostate tuberculosis were analyzed retrospectively. The mean age of the patients was...
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Prognostic significance of lymphovascular space invasion in patients with endometrioid endometrial cancer: a retrospective study from a single center

Dai Y, Dong Y, Cheng Y, Hou H, Wang J, Wang Z, Wang J

Objective: This study aims to analyze factors associated with lymphovascular space invasion (LVSI) and evaluate the prognostic significance of LVSI in Chinese endometrioid endometrial cancer (EEC) patients. Methods: Five-hundred eighty-four EEC...
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Association between Plasma Osmolality and Case Fatality within 1 Year after Severe Acute Ischemic Stroke

Liu M, Deng Y, Cheng Y, Hao Z, Wu S, Liu M

Purpose: Plasma osmolality, a marker of dehydration, is associated with cardiovascular mortality. We aimed to investigate whether elevated plasma osmolality is associated with case fatality within 1 year after severe...
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Identification of an immune-related risk signature and nomogram predicting the overall survival in patients with endometrial cancer

Cheng Y, Li X, Dai Y, Dong Y, Yang X, Wang J

Objective: Aimed to construct an immune-related risk signature and nomogram predicting endometrial cancer (EC) prognosis. Methods: An immune-related risk signature in EC was constructed using the least absolute shrinkage and selection...
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Outcomes of Hand-Assisted Laparoscopic Surgery for Colorectal Disease in an Emergency Setting

Kim Y, Cheng Y, Lee D, Kim HO, Kim H, Chun HK, Jung KU

PURPOSE: Laparoscopic surgery is accepted as a standard alternative to open procedures in the management of both benign and malignant colorectal disease. However, the safety and efficacy of the laparoscopic...
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Combination of High-Density Lipoprotein Cholesterol and Lipoprotein(a) as a Predictor of Collateral Circulation in Patients With Severe Unilateral Internal Carotid Artery Stenosis or Occlusion

Ma S, Zhang M, Qu H, Cheng Y, Du S, Fan J, Yao Q, Zhang X, Chen M, Zhang N, Shi K, Huang Y, Zhan S

Background and Purpose Collateral circulation is considered an important factor affecting the risk of stroke, but the factors that affect collateral circulation remain unclear. This study was performed to identify...
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Renormalization of Thalamic Sub-Regional Functional Connectivity Contributes to Improvement of Cognitive Function after Liver Transplantation in Cirrhotic Patients with Overt Hepatic Encephalopathy

Cheng Y, Li JL, Zhou JM, Zhang GY, Shen W, Zhang XD

Objective: The role of preoperative overt hepatic encephalopathy (OHE) in the neurophysiological mechanism of cognitive improvement after liver transplantation (LT) remains elusive. This study aimed to explore changes in sub-regional...
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Management Strategy for Congenital Choledochal Cyst with Co-existing Intrahepatic Dilation and Aberrant Bile Duct As Well As Other Complicated Biliary Anomalies

Dong Q, Jiang B, Zhang H, Jiang Z, Lu H, Yang C, Cheng Y, Hao X

The purpose of this study was to investigate and discuss imaging methods and management strategies for congenital choledochal cyst with co-existing intrahepatic dilation and aberrant bile duct as well as...
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Definitive extended field intensity-modulated radiotherapy and concurrent cisplatin chemosensitization in the treatment of IB2-IIIB cervical cancer

Zhang G, He F, Fu C, Zhang Y, Yang Q, Wang J, Cheng Y

OBJECTIVE: To assess the toxicity of delivering extended field intensity-modulated radiotherapy (EF-IMRT) and concurrent cisplatin chemotherapy for locally advanced cervical carcinoma. METHODS: Forty-five patients who underwent EF-IMRT and concurrent cisplatin chemotherapy...
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Effects of echinomycin on endothelin-2 expression and ovulation in immature rats primed with gonadotropins

Wang Z, Zhang Z, Wu Y, Chen L, Luo Q, Zhang J, Chen J, Luo Z, Huang X, Cheng Y

  • KMID: 1506225
  • Exp Mol Med.
  • 2012 Oct;44(10):615-621.
Echinomycin is a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity, which plays a crucial role in ovarian ovulation in mammalians. The present study was designed to test the hypothesis that...
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VEGF Promoter Polymorphism Confers an Increased Risk of Pulmonary Arterial Hypertension in a Chinese Population

Zhuo Y, Zeng Q, Zhang P, Li G, Xie Q, Cheng Y

PURPOSE: Evidence on the contribution of genes to the hereditary predisposition to pulmonary arterial hypertension (PAH) is limited. MATERIALS AND METHODS: In this study, we hypothesized that single nucleotide variants in...
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Impact of Liver Fibrosis and Fatty Liver on T1rho Measurements: A Prospective Study

Xie S, Li Q, Cheng Y, Zhang Y, Zhuo Z, Zhao G, Shen W

OBJECTIVE: To investigate the liver T1rho values for detecting fibrosis, and the potential impact of fatty liver on T1rho measurements. MATERIALS AND METHODS: This study included 18 healthy subjects, 18 patients...
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Brain Regional Homogeneity Changes in Cirrhotic Patients with or without Hepatic Encephalopathy Revealed by Multi-Frequency Bands Analysis Based on Resting-State Functional MRI

Zhang G, Cheng Y, Shen W, Liu B, Huang L, Xie S

OBJECTIVE: To investigate brain regional homogeneity (ReHo) changes of multiple sub-frequency bands in cirrhotic patients with or without hepatic encephalopathy using resting-state functional MRI. MATERIALS AND METHODS: This study recruited 46...
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Characterization of Caveola-Vesicle Complexes (CVCs) Protein, PHIST/CVC-81₉₅ in Plasmodium vivax

Wang B, Lu F, Han JH, Lee SK, Cheng Y, Nyunt MH, Ha KS, Hong SH, Park WS, Han ET

Plasmodium vivax produces numerous caveola-vesicle complex (CVC) structures beneath the membrane of infected erythrocytes. Recently, a member helical interspersed subtelomeric (PHIST) superfamily protein, PcyPHIST/CVC-81₉₅, was identified as CVCs-associated protein in...
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Cloning, expression and functional analysis of the duck Toll-like receptor 5 (TLR5) gene

Cheng Y, Sun Y, Wang H, Shi S, Yan Y, Li J, Ding C, Sun J

Toll-like receptor 5 (TLR5) is responsible for the recognition of bacterial flagellin in vertebrates. In the present study, the first TLR5 gene in duck was cloned. The open reading frame...
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