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BRCA1/2 mutation status in patients with metachronous breast and ovarian malignancies: clues towards the implementation of genetic counseling

Chao A, Lin YH, Yang LY, Wu RC, Chang WY, Chang PY, Chang SC, Lin CY, Huang HJ, Lin CT, Chou HH, Huang KG, Kuo WL, Chang TC, Lai CH

Objective: The characteristics of patients with metachronous breast and ovarian malignancies and the pathogenic role of BRCA1/2 mutations remain poorly understood. We investigated these issues through a review of hospital...
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Maintenance of pegylated liposomal doxorubicin/carboplatin in patients with advanced ovarian cancer: randomized study of an Asian Gynecologic Oncology Group

Lai CH, Vallikad E, Lin H, Yang LY, Jung SM, Liu HE, Ou YC, Chou HH, Lin CT, Huang HJ, Huang KG, Qiu J, Hung YC, Wu TI, Chang WY, Tan KT, Lin CY, Chao A, Chang CJ

Objectives: An Asian Gynecologic Oncology Group phase III randomized trial was conducted to determine whether maintenance chemotherapy could improve progression-free survival (PFS) in stages III/IV ovarian cancer. Methods: Between 2007 and...
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Prognostic Significance of EPHB2 Expression in Colorectal Cancer Progression

Jang BG, Kim HS, Chang WY, Bae JM, Kang GH

BACKGROUND: A receptor tyrosine kinase for ephrin ligands, EPHB2, is expressed in normal colorectal tissues and colorectal cancers (CRCs). The aim of this study was to investigate EPHB2 expression over...
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What is the Meaning of Anaphase-Promoting Complex 7 in Malignant Neoplasms?

Chang WY

No abstract available.
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Aurora Kinase A Is a Prognostic Marker in Colorectal Adenocarcinoma

Koh HM, Jang BG, Hyun CL, Kim YS, Hyun JW, Chang WY, Maeng YH

BACKGROUND: Aurora kinase A (AURKA), or STK15/BTAK, is a member of the serine/threonine kinase family and plays important roles in mitosis and chromosome stability. This study investigated the clinical significance...
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The Effect of (1S,2S,3E,7E,11E)-3,7,11,15-Cembratetraen-17,2-Olide (LS-1) from Lobophyyum sp. on the Apoptosis Induction of SNU-C5 Human Colorectal Cancer Cells

Kim EJ, Kang JI, Tung NH, Kim YH, Hyun JW, Koh YS, Chang WY, Yoo ES, Kang HK

(1S,2S,3E,7E,11E)-3,7,11,15-cembratetraen-17,2-olide (LS-1), a marine cembrenolide diterpene, has anticancer activity against colon cancer cells such as HT-29, SNU-C5/5-FU (fluorouracil-resistant SNU-C5) and SNU-C5. However, the action mechanism of LS-1 on SNU-C5 human...
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How Can We Ameliorate the Role of Colorectal Cancer Awareness Month?

Chang WY

No abstract available.
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Solitary Rectal Ulcer Syndrome Mimicking Rectal Cancer

Choi YM, Song HJ, Kim MJ, Chang WY, Kim BS, Hyun CL

Solitary rectal ulcer syndrome (SRUS) is a rare benign and chronic rectal disease that has a wide spectrum of clinical presentations and variable endoscopic findings. It is usually diagnosed by...
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Single Cavernous Hemangioma of the Small Bowel Diagnosed by Using Capsule Endoscopy in a Child with Chronic Iron-Deficiency Anemia

Bae SJ, Hwang G, Kang HS, Song HJ, Chang WY, Maeng YH, Kang KS

Cavernous hemangiomas of the gastrointestinal tract are extremely rare. In particular, the diagnosis of small bowel hemangiomas is very difficult in children. A 13-year-old boy presented at the outpatient clinic...
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The 2013-2015 Ebola outbreak in West Africa

Kang JH, Chang WY, Choi S, Rho J, Lee KH

Zaire Ebola virus (EBOV) is a fatal human pathogen, with a high case fatality rate (CFR) averaging up to 78%. In March 2014, the World Health Organization (WHO) was made...
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Analysis of Symptoms and Provided Services in Home-Based Cancer Patients

Kim WJ, Kim MY, Chang WY

PURPOSE: This study was to identify symptoms and provided services of home-based cancer patients in J province. METHODS: 1,350 data poins for 167 home-based cancer patients were analyzed retrospectively. 13 symptoms...
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Retention of the Mother and Child Health Handbook and Additional Immunization of Japanese Encephalitis and Tetanus Vaccine

Kim HK, Nam JE, Chang WY, Rho YK, Choi MK

BACKGROUND: Improvement of additional immunization rate is indicated as an important factor for effective immunization of diseases. In this study, the relationship between retention of mother and child health handbook...
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Massive Life-threatening Lower Gastrointestinal Hemorrhage Caused by an Internal Hemorrhoid in a Patient Receiving Antiplatelet Therapy: A Case Report

Kim M, Song HJ, Kim S, Cho YK, Kim HU, Song BC, Chang WY, Kim SH

A Dieulafoy lesion in the rectum is a very rare and it can cause massive lower gastrointestinal bleeding. An 83-year-old man visited our hospital. He had chronic constipation and had...
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Needs and Satisfaction of Cancer Patients on the Medical Services in Jeju Special Self-Governing Province

Kim WJ, Kim MY, Chang WY, Choi JH

  • KMID: 2305359
  • Korean J Hosp Palliat Care.
  • 2010 Sep;13(3):153-160.
PURPOSE: The purpose of the present study was to investigate needs and satisfaction on the medical services of cancer patients in Jeju Special Self-Governing Province. METHODS: Total 174 cancer patients, who...
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A Case of Peutz-Jeghers Syndrome Diagnosed by Wireless Capsule Endoscopy

Jeong SU, Song HJ, Choi EK, Cho YK, Kim HU, Song BC, Chang WY, Maeng YH

Peutz-Jeghers syndrome (PJS), is a rare autosomal dominant hereditary disorder. Intestinal hamartomatous polyps in association with melanocytic pigmentation of the skin and mucous membranes characterize PJS. Patients with PJS often...
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Endoscopic Versus Mini.open Carpal Tunnel Release in Patients with Bilateral Carpal Tunnel Syndrome

Chang WY, Han YM, Jang KS, Jang DK, Park SK, Chung DS, Park YS

  • KMID: 2070909
  • Korean J Spine.
  • 2009 Jun;6(2):68-74.
OBJECTIVE: The purpose of this study was to determine any differences in outcome and patient satisfaction between endoscopic release (ECTR) and open carpal tunnel release (OCTR) in patients with bilateral...
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Clinicopathological Analysis of Solid Pseudopapillary Tumor (SPT) of the Pancreas

Chung JC, Choi SH, Jang KT, Chang WY, Jo SH, Heo JS, Choi DW, Kim YI

  • KMID: 2096327
  • J Korean Surg Soc.
  • 2006 May;70(5):385-389.
PURPOSE: Solid pseudopapillary tumor (SPT) of the pancreas is a rare benign or low-grade pancreatic neoplasm with distinct clinicopathologic features. The purpose of this study was to evaluate the clinical...
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Expression of S100A4 in Invasive Adenocarcinoma and Intraductal Papillary Mucinous Neoplasm of the Pancreas

Moon HJ, An JY, Chang WY, Jang KT, Heo JS, Choi SH, Kim YI

  • KMID: 2244280
  • Korean J Hepatobiliary Pancreat Surg.
  • 2004 Jun;8(2):92-97.
PURPOSE: A pancreatic ductal adenocarcinoma is one of the most fatal cancers, as the majority of the patients present with locally advanced or metastatic tumors in the late stages of...
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Delayed Gastrointestinal Bleeding from Traumatic Superior Mesenteric Artery Pseudoaneurysm

Kim KS, Chang WY, Lee CH, Choi KM, Her KH

  • KMID: 2096181
  • J Korean Surg Soc.
  • 2004 Jun;66(6):523-525.
Acute onset of shock presented in a 23 years old male patient due to gastrointestinal bleeding. He had been in a car crash 49 days before presentation. On initial presentation,...
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Is Routine Chest X-ray Useful in Detection of Pulmonary Metastases after Curative Resection for Colorectal Carcinoma?

Yun SH, Park SB, Kang SJ, Park CM, Jeong KW, Chang WY, Lee WY, Chun HK

  • KMID: 1835448
  • J Korean Soc Coloproctol.
  • 2004 Jun;20(3):169-175.
PURPOSE: This study was performed to evaluate the effectiveness of conventional chest radiography and abdominal CT for early detection of pulmonary metastases after curative surgery for colorectal cancer. METHODS: We retrospectively...
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