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Eupafolin Suppresses P/Q-Type Ca2+ Channels to Inhibit Ca2+ / Calmodulin-Dependent Protein Kinase II and Glutamate Release at Rat Cerebrocortical Nerve Terminals

Chang A, Hung CF, Hsieh PW, Ko HH, Wang SJ

Eupafolin, a constituent of the aerial parts of Phyla nodiflora, has neuroprotective property. Because reducing the synaptic release of glutamate is crucial to achieving pharmacotherapeutic effects of neuroprotectants, we investigated...
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Palliative and end-of-life care in the emergency department

Chang A, Espinosa J, Lucerna A, Parikh N

With current medical advances, the human population continues to age. This presents healthcare practitioners with the increasing complexity of providing care to elderly patients with multifactorial medical and personal needs....
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Successful Closure of a Benign Refractory Tracheoesophageal Fistula Using an Over-the-Scope Clip after Failed Esophageal Stent Placement and Surgical Management

Pausawasdi N, Angkurawaranon C, Chantarojanasiri T, Chang A, Wongkornrat W, Leelakusolvong S, Methasate A

Tracheoesophageal fistulas (TEFs) have traditionally been managed surgically, but the endoscopic approach is widely performed as a less invasive alternative. Different closure techniques have been proposed with inconsistent results. An...
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Benefits of focus group discussions beyond online surveys in course evaluations by medical students in the United States: a qualitative study

Brandl K, Rabadia SV, Chang A, Mandel J

In addition to online questionnaires, many medical schools use supplemental evaluation tools such as focus groups to evaluate their courses. Although some benefits of using focus groups in program evaluation...
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Effects of an Empowerment Program on the Adjustment of Older Adults to Nursing Home Life

Chang A, Park YH

PURPOSE: This study aimed to evaluate the effectiveness of the empowerment intervention on the levels of self-esteem, interpersonal relationships and adjustment to nursing home life of the Korean nursing home...
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Comparison of Comprehensive Health Status and Health-related Quality of Life between Institutionalized Older Adults and Community Dwelling Older Adults

Hyun HJ, Chang A, Yu SJ, Park YH

PURPOSE: The aim of this study was to compare the factors of health-related quality of life in older adults according to the type of residency. METHODS: A cross-sectional comparative study was...
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SERPINE1 as an Independent Prognostic Marker and Therapeutic Target for Nicotine-Related Oral Carcinoma

Guo X, Sun Z, Chen H, Ling J, Zhao H, Chang A, Zhuo X

Objectives. Nicotine is an ingredient of tobacco, and exposure to nicotine increases the risks of various cancers, including oral cancer. Previous studies have focused on the addictive properties of nicotine,...
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Prospective Comparison of the AIMS65 Score, Glasgow-Blatchford Score, and Rockall Score for Predicting Clinical Outcomes in Patients with Variceal and Nonvariceal Upper Gastrointestinal Bleeding

Chang A, Ouejiaraphant C, Akarapatima K, Rattanasupa A, Prachayakul V

Background/Aims: This study aimed to determine the performance of the AIMS65 score (AIMS65), Glasgow-Blatchford score (GBS), and Rockall score (RS) in predicting outcomes in patients with upper gastrointestinal bleeding (UGIB),...
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Timing and Predictors of Recanalization After Anticoagulation in Cerebral Venous Thrombosis

Salehi Omran S, Shu L, Chang A, Parikh NS, Zubair AS, Simpkins AN, Heldner MR, Hakim A, Kasab SA, Nguyen T, Klein P, Goldstein ED, Vedovati MC, Paciaroni M, Liebeskind DS, Yaghi S, Cutting S

Background and Purpose Vessel recanalization after cerebral venous thrombosis (CVT) is associated with favorable outcomes and lower mortality. Several studies examined the timing and predictors of recanalization after CVT with...
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