- Comparative Analysis of the Three Classes of Archaeal and Bacterial Ribonucleotide Reductase from Evolutionary Perspective
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Pangare MG, Chandra SB
- KMID: 1806199
- Genomics Inform.
- 2010 Dec;8(4):170-176.
The Ribonucleotide reductases (RNR) are essential enzymes that catalyze the conversion of nucleotides to deoxynucleotides in DNA replication and repair in all living organisms. The RNRs operate by a free... -
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- Bioinformatics Analysis of Hsp20 Sequences in Proteobacteria
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Heine M, Chandra SB
- KMID: 2166438
- Genomics Inform.
- 2009 Mar;7(1):26-31.
Heat shock proteins are a class of molecular chaperones that can be found in nearly all organisms from Bacteria, Archaea and Eukarya domains. Heat shock proteins experience increased transcription during... -
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- Significance of Cellular Senescence in Aging and Cancer
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Grimes A, Chandra SB
- KMID: 1972671
- Cancer Res Treat.
- 2009 Dec;41(4):187-195.
Cellular senescence is a mechanism that induces an irreversible growth arrest in all somatic cells. Senescent cells are metabolically active but lack the capacity to replicate. Evolutionary theories suggest that... -
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- A Comparative Analysis of Monofunctional Biosynthetic Peptidoglycan Transglycosylase (MBPT) from Pathogenic and Non-pathogenic Bacteria
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Baker AT, Takahashi , Chandra SB
- KMID: 2166479
- Genomics Inform.
- 2010 Jun;8(2):63-69.
Monofunctional biosynthetic peptidoglycan transglycosylase (MBPT) catalyzes the formation of the glycan chain in bacterial cell walls from peptidoglycan subunits: N-acetylglucosamine (NAG) and acetylmuramic acid (NAM). Bifunctional glycosyltransferases such as the... -
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- Sequence Analysis and Potential Action of Eukaryotic Type Protein Kinase from Streptomyces coelicolor A3(2)
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Roy DR, Chandra SB
- KMID: 2166321
- Genomics Inform.
- 2008 Mar;6(1):44-49.
Protein kinase C (PKC) is a family of kinases involved in the transduction of cellular signals that promote lipid hydrolysis. PKC plays a pivotal role in mediating cellular responses to... -
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