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Dens Fracture-Nonunion in Ankylosing Spondylitis: A Case Report

Cho WJ, Chae JW, Ryu JS, Park JC, Chang H

Patients with ankylosing spondylitis are susceptible to fractures, which usually occur in the cervical spine. However, upper spinal fractures, particularly dens fracture-nonunion complicating ankylosing spondylitis, are quite rare. We encountered...
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A simple time-to-event model with NONMEM featuring right-censoring

Tran QT, Chae Jw, Bae KS, Yun Hy

In healthcare situations, time-to-event (TTE) data are common outcomes. A parametric approach is often employed to handle TTE data because it is possible to easily visualize different scenarios via simulation....
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Case of Staphylococcus schleiferi Vascular Access Infections with a Hemodialysis Patient

Chae JW, Yu SN, Lee EJ

Staphylococcus schleiferi has been infrequently reported as a human pathogen. We experienced the case of vascular access infection by Staphylococcus schleiferi in a 65-year-old hemodialysis patient. Metastatic infection occurred despite...
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Synovial Osteochondromatosis of the Subtalar Joint in an Adolescent Baseball Player

Chae JW, Cho HL, Oh YS, Lee WS

Synovial chondromatosis is an uncommon disorder characterized by cartilaginous proliferation within the synovial membrane of the articular joint. Smaller joints are rarely affected and it may be progressed to osteochondromatosis...
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Influence of Oxygen to Population Pharmacokinetics/Pharmacodynamics of Alcohol in Healthy Volunteers

Song B, Back HM, Hwang SY, Chae JW, Yun HY, Kwon KI

OBJECTIVE: To develop a population pharmacokinetics (PK)/pharmacodynamics (PD) model for alcohol in healthy volunteers and to elucidate individual characteristics to affects alcohol's PK or PD including dissolved oxygen. METHODS: Following multiple...
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Primary Antiphospholipid Syndrome Presenting as Bell Palsy without Cerebral Arterial Thrombosis

Kim BY, Chae JW, Kim HS

Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by the presence of antiphospholipid antibodies with vascular thrombosis or increasing pregnancy-related morbidity. The risk of thrombotic events, including cerebral arterial thrombosis,...
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Cervical Myelopathy Secondary to Atlas Hypoplasia: Reports of 3 Adult Cases

Chang H, Cho WJ, Park JB, Moon MS, Chae JW, Ryu JS, Kang HS

There have been paucity of reports on atlas hypoplasia, and as a result this condition is not clearly defined, nor well understood. The authors reported three cases of atlas hypoplasia...
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A Case of Plummer-Vinson Syndrome

Chae JW, Jung HW, Lee JH, Rhee PL, Kim JJ, Paik SW, Rhee JC

  • KMID: 1572976
  • Korean J Gastrointest Endosc.
  • 2004 Feb;28(2):67-70.
The combination of symptomatic hypopharyngeal webs and iron-deficiency anemia in middle-aged women constitutes Plummer-Vinson syndrome. It is uncommon but important syndrome because of inceased risk of squamous cell carcinoma of...
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Spinal Stenosis Due to Hypertrophy of the Ligament Flavum with Monosodium Urate Deposits

Park JB, Kim SG, Choi WS, Maeng LS, Chae JW, Chang H

  • KMID: 2336064
  • J Korean Orthop Assoc.
  • 1998 Jun;33(3):802-806.
Deposition of monosodium urate crystal in joints and periarticular soft tissue is regarded as one of the characteristics of chronic gouty arthritis. In spine, however, only nineteen cases of tophaceous...
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Epidural Arteriovenous Fistula in the Cervical Spine Associated with Unilateral Upper Extremity Pain: A Case Report

Chae JW, Chang H, Nam HJ, Moon MS

We experienced a rare case of an epidural arteriovenous fistula, which presented with symptoms similar to those of cervical radiculopathy. An 18-years-old woman suffered from neck pain, which radiated to...
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A case of chronic diarrhea caused by duodenocolic fistula

Kim J, Chae JW, Suh HJ, Lee JH, Kim YH, Rhee JC, Huh JS

  • KMID: 1927297
  • Korean J Med.
  • 2004 Nov;67(Suppl 3):S718-S721.
The four basic mechanisms that cause chronic diarrhea are osmotic, secretory and exudative factors, and abnormal intestinal transit. A gastrointestinal fistula cause chronic diarrhea by abnormal intestinal transit, and it...
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Compatibility Study between Physiologically Based Pharmacokinetic (PBPK) and Compartmental PK Model Using Lumping Method: Application to the Voriconazole Case

Ryu Hj, Kang Wh, Chae Jw, Yun Hy

Background: Generally, pharmacokinetics (PK) models could be stratified into two models. The compartment PK model uses the concept of simple compartmentalization to describe complex bodies, and the physiologically based pharmacokinetic...
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Free Vascularized Fibular Graft for Femoral Head Collapse Combined with Ununited Pathologic Intertrochanteric Fracture

Kim HM, Cho HL, Lee JY, Chae JW, Shin MJ, Kim JU

Surgery for pathologic hip fracture poses significant challenges regarding the fixation of fracture and management of the original tumor lesion. An extensive destruction of the femoral neck and intertrochanteric region...
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Mono-segment Cervical Spondylotic Myelopathy

Ryu JS, Chae JW, Cho WJ, Moon MS, Chang H

  • KMID: 2322929
  • J Korean Soc Spine Surg.
  • 2006 Dec;13(4):234-239.
STUDY DESIGN: A retrospective follow-up study comparing soft disc cervical myelopathy (Group A) and spondylotic bar cervical myelopathy (Group B). OBJECTIVES: To analyze different factors by comparing preoperative radiological and clinical...
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Two Cases of Aspergillus Endocarditis in Patients with Acute Lymphoblastic Leukemia

Shin SC, Peck KR, Hong JJ, Song BG, Kim DH, Jeon K, Chae JW, Son JS, Jung SI, Oh WS, Song JH

  • KMID: 2170080
  • Infect Chemother.
  • 2003 Oct;35(5):332-336.
Although Aspergillus endocarditis has rarely been reported, it can cause fatal complications in hematologic malignancy patients and allogeneic stem cell transplant recipients. We experienced two cases of aspergillus endocarditis developed...
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Analysis of Pembrolizumab-induced Blood Glucose Level Change in Cancer Patients

Jung HY, Hong MS, Jung WJ, Choi SO, Chae Jw, Yun Hy

Background: Pembrolizumab, an anti-cancer drug, is known to increase the activity of the immune system, leading to side effects called immune-related adverse events (irAE), including type 1 diabetes. This study...
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Anatomical Reduction with Brick-Work Technique in Comminuted Intraarticular Distal Radius Fractures

Kim HM, Cho HL, Chae JW, Shin MJ

PURPOSE: This study examined the clinical outcomes of comminuted intraarticular distal radius fractures treated by an anatomical reduction using a brick-work technique. MATERIALS AND METHODS: Seventeen patients with AO/OTA type 23-C3...
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Medication Use Evaluation of Denosumab in Postmenopausal Women with Osteoporosis or Osteopenia

Lim SH, Jung WJ, Chae Jw, Kang C, Yun Hy

Background: The indication of denosumab for osteoporosis was expanded from second-line to first-line therapy in 2019. The aim of this study was to evaluate the efficacy of denosumab as both...
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The Role of Spinal Dopaminergic Transmission in the Analgesic Effect of Nefopam on Rat Inflammatory Pain

Kim DY, Chae JW, Lim CH, Heo BH, Park KS, Lee HG, Choi JI, Yoon MH, Kim WM

BACKGROUND: Nefopam has been known as an inhibitor of the reuptake of monoamines, and the noradrenergic and/or serotonergic system has been focused on as a mechanism of its analgesic action....
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The Relationship Between Adiposity and Risk factors for Cadiovascular Disease at Normal Body Weight Male

Kwon WS, Kim JS, Chae JW, Lee KM, Jung SP, Moon Y

BACKGROUND: Most of all studies about the relation between the health risk and obesity are based on the European and American data. The purpose of this study is to examine...
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