- Fraxetin Induces Heme Oxygenase-1 Expression by Activation of Akt/Nrf2 or AMP-activated Protein Kinase α/Nrf2 Pathway in HaCaT Cells
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Kundu J, Chae IG, Chun KS
- KMID: 2367571
- J Cancer Prev.
- 2016 Sep;21(3):135-143.
- doi: 10.15430/JCP.2016.21.3.135
BACKGROUND: Fraxetin (7,8-dihydroxy-6-methoxy coumarin), a coumarin derivative, has been reported to possess antioxidative, anti-inflammatory and neuroprotective effects. A number of recent observations suggest that the induction of heme oxygenase-1 (HO-1)... -
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