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Protective Role of Prx(Peroxiredoxin) I and II against H2O2-Induced Apoptosis of MCF7 Cell Lines

Ahn SJ, Bae JY, Lee RA, Han W, Kim SW, Chae HZ, Noh DY

PURPOSE: Apoptosis is known to be induced either by direct oxidative damage from oxygen free radicals or hydrogen peroxide, or from their generation in cells by injurious agents. Peroxiredoxin plays...
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Altered expression of Peroxiredoxin and Thioredoxin in septic animal model

Kim HJ, Chae HZ, Ahn CM, Kim SK, Lee WY

  • KMID: 2318226
  • Tuberc Respir Dis.
  • 1999 Oct;47(4):451-459.
BACKGROUND: In sepsis, excessive generation of reactive oxygen species plays key roles in the pathogenesis of acute lung injury. The serum antioxidants such as catalase and MnSOD are elevated in...
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Distribution of Thioredoxin Peroxidases and Expression of Thioredoxin Peroxidases in Various Human Cancers

Kim HJ, Hwang SC, Noh DY, Kim SK, Lee WY, Chae HZ, Rhee SG

  • KMID: 2306383
  • Korean J Med.
  • 1997 Feb;52(2):165-173.
OBJECTIVES: Thioredoxin peroxidase(TPx), which does not exhibit similar activity and amino acid sequence homology to conventional antioxidant enzymes has been purified from S cerevisiae and bovine brain. Natural killer enhancing...
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