- Alterations of CDKN2 (MTS1/p16INK4A) gene in paraffin-embedded tumor tissues of human stomach, lung, cervix and liver cancers
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Kim JR, Kim SY, Kim MJ, Kim JH
- KMID: 754996
- Exp Mol Med.
- 1998 Jun;30(2):109-114.
The CDKN2 (MTS1/p16INK4A) gene, encoding cyclin dependent kinase inhibitor, was found to be homozygously deleted at a high frequency in cell lines from many different types of cancer and some primary cancers.... -
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- Analysis of clonality by X chromosome inactivation in uterine cervix cancer
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Ko HM, Choi C, Park CS, Juhng SW
- KMID: 1081054
- J Korean Med Sci.
- 1997 Aug;12(4):322-326.
- doi: 10.3346/jkms.1997.12.4.322
The determination of a unicellular or a multicellular origin of a tumor is an important due for understanding its etiology. To investigate this issue, we performed clonality assay of... -
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- p53 codon 72 polymorphism and risk of cervical carcinoma in Korean women
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Baek WK, Cho JW, Suh SI, Suh MH, Shin DH, Cho CH, Lee TS, Cha SD
- KMID: 1731236
- J Korean Med Sci.
- 2000 Feb;15(1):65-67.
- doi: 10.3346/jkms.2000.15.1.65
A common polymorphism of the wild type p53 is known at codon 72 of exon 4, with 2 alleles encoding either arginine (CGC, p53Arg) or proline (CCC, p53Pro). A recent... -
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- Molecular genetics of gynecologic cancer
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Whang JD, Lee JH
- KMID: 1081028
- J Korean Med Sci.
- 1997 Oct;12(5):383-389.
- doi: 10.3346/jkms.1997.12.5.383
During the past decades, the expansion of molecular biology has had a pivotal role in understanding the basis of cancer development and progression. In addition, real advances have been... -
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- Role of human papillomavirus and p53 tumor suppressor gene in cervical carcinogenesis
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Kim KH, Kim YS
- KMID: 1093805
- Yonsei Med J.
- 1995 Oct;36(5):412-425.
- doi: 10.3349/ymj.1995.36.5.412
To determine whether the dysfunction of p53 protein, caused either by the mutation of p53 gene itself or by the human papillomavirus (HPVs) is involved in the development of cervical... -
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- HPV E6 antisense induces apoptosis in CaSki cells via suppression of E6 splicing
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Cho CW, Poo H, Cho YS, Cho MC, Lee KA, Lee SJ, Park SN, Kim IK, Jung YK, Choe YK, Yeom YI, Choe IS, Yoon DY
- KMID: 1081466
- Exp Mol Med.
- 2002 May;34(2):159-166.
Cervical cancer is known to be highly associated with viral oncogene E6 and E7 of human papilloma virus. Down-regulation of oncogene expression by antisense-based gene therapy has been extensively studied.... -
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