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Lineage conversion of mouse fibroblasts to pancreatic α-cells

Liu T, Sun L, Jiang B, Li L, Cen J, Chen X, Zhang Z, Wang Q, Cheng X, Shi Y, Hui L

α-cells, which synthesize glucagon, also support β-cell survival and have the capacity to transdifferentiate into β-cells. However, the role of α-cells in pathological conditions and their putative clinical applications remain...
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