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Docetaxel-loaded PLGA nanoparticles to increase pharmacological sensitivity in MDA-MB-231 and MCF-7 breast cancer cells

Tran P, Nguyen TN, Lee Y, Tran PN, Park JS

This study aimed to develop docetaxel (DTX) loaded poly(lactic-coglycolic acid) (PLGA) nanoparticles (DTX-NPs) and to evaluate the different pharmacological sensitivity of NPs to MCF-7 and MDA-MB-231 breast cancer cells. NPs...
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Effect of corosolic acid on apoptosis and angiogenesis in MDA-MB-231 human breast cancer cells

Son KH, Hwang Jh, Kim Dh, Cho YE

Purpose: Corosolic acid (CA), also known as 2α-hydroxyursolic acid, is present in numerous plants, and is reported to exhibit anti-cancer and anti-proliferative activities in various cancer cells such as osteosarcoma,...
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Expression of Estrogen Receptor-alpha in Nasal Polyps and the Effects of Dexamethasone on Estrogen Receptoralpha Expression in RPMI 2650 Cells

Ban WW, Lee YJ, Lee SH, Jung JY, Baek BJ

Background: Studies have reported that epithelial cell proliferation may be involved in the pathogenesis of nasal polyps (NPs). Estrogen receptor (ER)-α, one type of ER, is related to antiinflammatory action...
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Effects of dental acid etchants in oral epithelial cells

Kim DK, Kwak JW, Jo RM, Jung DS, Youn DY, Oh NY, Jang JH

Phosphoric acid (P.A.; 37%) can induce necrosis on the oral mucosa and cause the ulceration of periodontal tissue. However, most studies reported are clinical case studies, with few basic science...
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Anti-oxidant and Hepatoprotective Effect of White Ginsengs in H2O2-Treated HepG2 Cells

Parthasarathi S, Hong SC, Oh MH, Park YS, Yoo JH, Seol SY, Lee H, Park JD, Pyo MK

The antioxidant activity of white ginseng was not recorded in Korea Functional Food Code, while its activity of red ginsengs was recorded. The aim of this study was to evaluate...
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Comparison of the Effects of 13-cis Retinoic Acid and Melatonin on the Viabilities of SH-SY5Y Neuroblastoma Cell Line

Tosun M, Soysal Y, Mas NG, Karabekir

OBJECTIVE: Neuroblastoma is one of common childhood tumors. Although its mortality is very high, there is no effective treatment yet. The aim of this project is to evaluate cytotoxic effects...
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Non-Thermal Atmospheric-Pressure Plasma Possible Application in Wound Healing

Haertel B, von Woedtke T, Weltmann K, Lindequist U

Non-thermal atmospheric-pressure plasma, also named cold plasma, is defined as a partly ionized gas. Therefore, it cannot be equated with plasma from blood; it is not biological in nature. Non-thermal...
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Lactobacillus acidophilus Contributes to a Healthy Environment for Vaginal Epithelial Cells

Pi W, Ryu JS, Roh J

Lactobacillus species in the female genital tract are thought to act as a barrier to infection. Several studies have demonstrated that lactobacilli can adhere to vaginal epithelial cells. However, little...
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The Composition of the Root of Ixeris dentata var. albiflora Nakai. and Cell Viability and DPPH Radical Scavenging Activities of its Extract

Hong S, Jeong D, Kim K, Hwang E

Ixeris dentata var. albiflora Nakai, a herbal plant, is often used to make a strong stomach as an antiphlogistic used when dyspepsia and to improve appetite in Korea and China....
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Protective Effects of Epigallocatechin Gallate After UV Irradiation of Cultured Human Lens Epithelial Cells

Heo J, Lee BR, Koh JW

PURPOSE: To evaluate the protective effects of epigallocatechin gallate (EGCG) against UV irradiation of cultured human lens epithelial cells. METHODS: We irradiated cultured human lens epithelial cells with...
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An experimental study on fat cell viablity according to different harvesting techniques

Lee WD, Choi JY

  • KMID: 2184411
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2008 Jan;30(1):22-29.
PURPOSE: The purpose of this study is to test the efficacy of various methods of fat harvesting in animal model by viability comparison with assay including cell counting, MTT assay,...
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The Influence of Propofol on Cell Viability after Reoxygenation in Rat Embryonic Heart H9c2 Cells

Kim YH

BACKGROUND: Although reperfusion is a salvaging method for an acute myocardial infarction, the act of reperfusion itself can paradoxically result in reactive oxygen species (ROS) mediated myocyte death. Propofol has...
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Estimation of Liver Cell Viability after Ischemia and Reperfusion Injury in Rat Liver

Park SH, Yun SS, Lee DS, Kim HJ, Choi JH, Kim JY

  • KMID: 2325111
  • J Korean Surg Soc.
  • 2007 Jul;73(1):1-7.
PURPOSE: Liver cell damage after ischemia and reperfusion injury has been a major cause of death after liver surgery. Yet there have been no exact and practical guidelines for assessing...
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In Vitro Study of Tumor Seeking Radiopharmaceutical Uptake by Human Breast Cancer Cell Line MCF-7 after Paclitaxel Treatment

Choi JY, Choi Y, Choe YS, Lee KH, Kim BT

  • KMID: 1512506
  • Nucl Med Mol Imaging.
  • 2007 Oct;41(5):364-372.
PURPOSE: This study was designed to investigate the cellular uptake of various tumor imaging radiopharmaceuticals in human breast cancer cells before and after paclitaxel exposure considering viable cell number. MATERIALS AND...
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Proper Condition of Centrifugation for the Fat Cell Viability in the Autologous Fat Injection

Jang KM, Kim JY, Yang JD, Chung HY, Park JW, Cho BC

  • KMID: 2098426
  • J Korean Soc Plast Reconstr Surg.
  • 2006 Jul;33(4):423-426.
PURPOSE: In the autologous fat injection, the centrifugation is useful for the refinement of harvested fat. As it can be an injury to the fat cell, we studied the fat...
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Cell Viability and Proliferation Activity of Peripheral Lymphocytes in Patients with Alzheimer's Disease

Lee S, Kwon YA, Kim H, Chung SH, Jo S, Kim DK

  • KMID: 2341118
  • J Korean Neuropsychiatr Assoc.
  • 2005 Jul;44(4):497-504.
OBJECTIVES: There are evidences of apoptotic neuronal cell death in Alzheimer's disease (AD). Recent studies suggested AD pathogenesis in the central nervous system as well as in peripheral lymphocytes. The...
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The Comparison of Duration to Maintain Cell Viability for HLA-B27 Test According to Anticoagulants

Kim HS, Jearn LH, Kim TY

  • KMID: 1899472
  • J Korean Rheum Assoc.
  • 2004 Sep;11(3):247-253.
OBJECTIVE: HLA-B27 test require at least 80% of viable cells. So the procedures require immediate processing of the blood samples. To increase the efficiency and the cost-effectiveness of the laboratory,...
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Cytocompatibility of thermally oxidized Ti-Ag alloys

Kim HJ, Oh KT, Ee ZW, Kim KN, Han DH

  • KMID: 1809417
  • J Korean Acad Prosthodont.
  • 2004 Aug;42(4):333-343.
STATEMENT OF PROBLEM: In its preceding work, change in surface characteristics were investigated in consideration that both microtopograpy and macroscopic configuration of implants surface are two of the most important...
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MAPK Activation and Cell Viability after H2O2 Stimulation in Cultured Feline Ileal Smooth Muscle Cells

Song HJ, Jeong JH, Lee DK, Lee TS, Min YS, Sohn UD

  • KMID: 1611495
  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):339-344.
Recent data have shown the importance of oxidative stresses in the pathogenesis of inflammatory bowel disease, crohn's disease and ulcerative colitis. H2O2, reactive oxygen species (ROS) donor, has been reported...
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Neuroprotective Effect of Estrogen on Motor Neuron Cells Expressing Wild Type or Mutant Cu/Zn Superoxide Dismutase

Kim HJ, Park SH, Kim MH, Kim HJ, Lee KW

  • KMID: 2343020
  • J Korean Neurol Assoc.
  • 2002 Sep;20(5):525-529.
BACKGROUND: Recently, the mechanism involved in nitric oxide (NO)-mediated motor neuron death is under extensive investigation. The role of Cu/Zn superoxide dismutase (SOD) mutation, which is found in about 2%...
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