- The Role of Focal Adhesion Kinase in the TGF-beta-Induced Myofibroblast Transdifferentiation of Human Tenon's Fibroblasts
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Hong S, Lee JB, Iizuka Y, Song YK, Seong GJ, Han SH
- KMID: 1120181
- Korean J Ophthalmol.
- 2012 Feb;26(1):45-48.
- doi: 10.3341/kjo.2012.26.1.45
PURPOSE: To investigate the role of focal adhesion kinase (FAK) in transforming growth factor (TGF)-beta-induced myofibroblast transdifferentiation of human Tenon's fibroblasts. METHODS: Primary cultured human Tenon's fibroblasts were exposed to TGF-beta1... -
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- Adenovirus adenine nucleotide translocator-2 shRNA effectively induces apoptosis and enhances chemosensitivity by the down-regulation of ABCG2 in breast cancer stem-like cells
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Jang JY, Kim MK, Jeon YK, Joung YK, Park KD, Kim CW
- KMID: 1365902
- Exp Mol Med.
- 2012 Apr;44(4):251-259.
- doi: 10.3858/emm.2012.44.4.019
Cancer stem cells (CSCs) are resistant to chemo- and radio-therapy, and can survive to regenerate new tumors. This is an important reason why various anti-cancer therapies often fail to completely... -
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