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Hypoxia-inducible factor: role in cell survival in superoxide dismutase overexpressing mice after neonatal hypoxia-ischemia

Jeon GW, Sheldon RA, Ferriero D

BACKGROUND: Sixty percent of infants with severe neonatal hypoxic-ischemic encephalopathy die, while most survivors have permanent disabilities. Treatment for neonatal hypoxic-ischemic encephalopathy is limited to therapeutic hypothermia, but it does...
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G0/G1 Switch 2 Induces Cell Survival and Metastasis through Integrin-Mediated Signal Transduction in Human Invasive Breast Cancer Cells

Cho E, Kwon YJ, Ye DJ, Baek HS, Kwon TU, Choi HK, Chun YJ

Human breast cancer cell line, MDA-MB-231, is highly invasive and aggressive, compared to less invasive cell line, MCF-7. To explore the genes that might influence the malignancy of MDA-MB-231, DNA...
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The Long Non-Coding RNA CASC2 Suppresses Cell Viability, Migration, and Invasion in Hepatocellular Carcinoma Cells by Directly Downregulating miR-183

Sun J, Liu L, Zou H, Yu W

PURPOSE: Hepatocellular carcinoma (HCC) is the most common malignant tumor of liver cells. Researchers have reported that cancer susceptibility candidate 2 (CASC2), a long non-coding RNA, is down-regulated in various...
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Optimal Stem Cell Transporting Conditions to Maintain Cell Viability and Characteristics

Yu NH, Chun SY, Ha YS, Kim HT, Kim DH, Kim J, Chung JW, Lee JN, Song PH, Yoo ES, Kim BS, Kwon TG

BACKGROUND: The preservation of stem cell viability and characteristics during cell transport from the bench to patients can significantly affect the success of cell therapy. Factors such as suspending medium,...
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Selective Mitochondrial Uptake of MKT-077 Can Suppress Medullary Thyroid Carcinoma Cell Survival In Vitro and In Vivo

Starenki D, Park JI

BACKGROUND: Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor mainly caused by mutations in the rearranged during transfection (RET) proto-oncogene. Not all patients with progressive MTC respond to current therapy...
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Evaluation of antibacterial activity and osteoblast-like cell viability of TiN, ZrN and (Ti(1-x)Zr(x))N coating on titanium

Ji MK, Park SW, Lee K, Kang IC, Yun KD, Kim HS, Lim HP

PURPOSE: The aim of this study was to evaluate antibacterial activity and osteoblast-like cell viability according to the ratio of titanium nitride and zirconium nitride coating on commercially pure titanium...
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Assessment of Cell Viability in Umbilical Cord Blood by Using 7-AAD/annexin V Dual Staining

Kim KM, Huh JY, Kang MS, Jung SH

  • KMID: 2312235
  • Lab Med Online.
  • 2014 Jan;4(1):1-7.
BACKGROUND: The quality of cord blood largely depends on cell viability. Viability assessments using trypan blue or 7-aminoactinomycin (7-AAD) staining, which are commonly used methods, may not reflect early apoptosis...
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The Influence of Propofol on Cell Viability after Reoxygenation in Rat Embryonic Heart H9c2 Cells

Kim YH

BACKGROUND: Although reperfusion is a salvaging method for an acute myocardial infarction, the act of reperfusion itself can paradoxically result in reactive oxygen species (ROS) mediated myocyte death. Propofol has...
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Estimation of Liver Cell Viability after Ischemia and Reperfusion Injury in Rat Liver

Park SH, Yun SS, Lee DS, Kim HJ, Choi JH, Kim JY

  • KMID: 2325111
  • J Korean Surg Soc.
  • 2007 Jul;73(1):1-7.
PURPOSE: Liver cell damage after ischemia and reperfusion injury has been a major cause of death after liver surgery. Yet there have been no exact and practical guidelines for assessing...
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Induction of Heme Oxygenase-1 by Traditional Herb Mix Extract Improves MKN-74 Cell Survival and Reduces Stomach Bleeding in Rats by Ethanol and Aspirin in vivo

Kang YJ, Moon HS, Kim HJ, Seo HG, Lee JH, Chang KC

  • KMID: 1512909
  • Korean J Physiol Pharmacol.
  • 2007 Apr;11(2):65-70.
Chinese herb medicines have traditionally been used to treat or alleviate the symptom of various diseases. The rationale for use of certain herbs to certain disorder is now getting unveiled...
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Evaluation of periodontal ligament cell viability in rat teeth according to various extra-oral dry storage times using MTT assay

Jeon IS, Kim ES, Kim J, Lee SJ

The purpose of this study was to verify the usefulness of MTT analysis as a tool of measurement of the periodontal ligament cell viability from the extracted rat molar. A total...
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A Promotive Effect of Low Level Laser on Hair Cell Viability in Postnatal Organotypic Culture of Rat Utricles

Chung YW, Ahn JC, Lim ES, Kim YS, Lee MY, Jung JY, Rhee CK

  • KMID: 1603823
  • J Korean Bal Soc.
  • 2006 Jun;5(1):29-34.
BACKGROUND AND OBJECTIVES: To culture and maintain mammalian hair cells is still a big challenge. In this study, long-term organotypic culture of rat utricular maculae was established to study vestibular...
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Evaluation of periodontal ligament cell viability in rat teeth after frozen preservation using in-vivo MTT assay

Kim JW, Kim ES, Kim J, Lee SJ

The purpose of this study was to examine the viability of PDL cells in rat molars by using in vivo MTT assay, which was used to compare fast cryopreservation group...
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The Cell Survival and Differentiation after Transplantation, Which Harvest from Adult Rat Brain by High-speed Centrifugation Method

Kim JT, Yoo DS, Woo JH, Huh PW, Cho KS, Kim DS

  • KMID: 1956341
  • J Korean Neurosurg Soc.
  • 2005 Aug;38(2):121-125.
OBJECTIVE: Many recent reports have shown that the mature mammalian brain harbors multipotent stem cells, rendering the brain capable of generating new neurons and glia throughout life. Harvested stem cells...
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Differential Inhibition of MPP+- or 6-Hydroxydopamine-induced Cell Viability Loss in PC12 Cells by Trifluoperazine and W-7

Lee CS

  • KMID: 1600082
  • Korean J Physiol Pharmacol.
  • 2005 Aug;9(4):247-253.
The present study assessed the effect of calmodulin antagonists trifluoperazine and W-7 against the cytotoxicity of MPP+ and 6-hydroxydopamine (6-OHDA) in relation to the mitochondrial dysfunction and cell death in...
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Cell Viability and Proliferation Activity of Peripheral Lymphocytes in Patients with Alzheimer's Disease

Lee S, Kwon YA, Kim H, Chung SH, Jo S, Kim DK

  • KMID: 2341118
  • J Korean Neuropsychiatr Assoc.
  • 2005 Jul;44(4):497-504.
OBJECTIVES: There are evidences of apoptotic neuronal cell death in Alzheimer's disease (AD). Recent studies suggested AD pathogenesis in the central nervous system as well as in peripheral lymphocytes. The...
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Effects of Heat Shock Protein 70 (HSP70) Induction after Lipopoly?saccharide Exposure on the IL-6 Production and the Cell Viability after Subsequent Lipopolysaccharide Challenge in Murine Alveolar Epithelial Cells

Lee JM, Kim JS, Kim YK, Kim SJ, Lee SY, Kwon SS, Park SH

  • KMID: 2318550
  • Tuberc Respir Dis.
  • 2005 Apr;58(4):375-384.
BACKGROUND AND AIMS: Pre-induction of heat shock protein 70 (HSP70) is known to effectively attenuate the lipopolysaccharide (LPS)-induced inflammatory response in lung tissue. However, it is unclear if HSP70 induction...
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MAPK Activation and Cell Viability after H2O2 Stimulation in Cultured Feline Ileal Smooth Muscle Cells

Song HJ, Jeong JH, Lee DK, Lee TS, Min YS, Sohn UD

  • KMID: 1611495
  • Korean J Physiol Pharmacol.
  • 2004 Dec;8(6):339-344.
Recent data have shown the importance of oxidative stresses in the pathogenesis of inflammatory bowel disease, crohn's disease and ulcerative colitis. H2O2, reactive oxygen species (ROS) donor, has been reported...
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The Comparison of Duration to Maintain Cell Viability for HLA-B27 Test According to Anticoagulants

Kim HS, Jearn LH, Kim TY

  • KMID: 1899472
  • J Korean Rheum Assoc.
  • 2004 Sep;11(3):247-253.
OBJECTIVE: HLA-B27 test require at least 80% of viable cells. So the procedures require immediate processing of the blood samples. To increase the efficiency and the cost-effectiveness of the laboratory,...
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Phosphorylation of Glycogen Synthase Kinase-3beta(S9) Induced Neuronal Cell Survival by Sulindac in the Rat Retina

Choi SM, Choi JS, Joo CK

  • KMID: 2206621
  • J Korean Ophthalmol Soc.
  • 2003 Mar;44(3):721-726.
PURPOSE: Inactivation of glycogen synthase kinase-3beta (GSK-3beta) by S9 phosphorylation is implicated in neuronal cell survival. In this study, we examined the involvement of GSK-3betaS9) phosphorylation on retina cell survival...
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