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The Transcription Factor Mist1 Regulates the Cellular Polarity in Mouse Pancreatic Acinar Cells

Yang YM, Lee SI, Shin DM

  • KMID: 2009498
  • Int J Oral Biol.
  • 2012 Mar;37(1):37-41.
Pancreatic acinar cells exhibit a polarity that is characterized by the localization of secretory granules at the apical membrane. However, the factors that regulate cellular polarity in these cells are...
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Polarized and Stage-Dependent Distribution of Immunoreactivity for Novel PDZ-Binding Protein Preso1 in Adult Neurogenic Regions

Lee ES, Kim WR, Kim Y, Lee HW, Kim H, Sun W

BACKGROUND: Adult neural stem cells have the potential for self-renewal and differentiation into multiple cell lineages via symmetric or asymmetric cell division. Preso1 is a recently identified protein involved in...
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Membrane Proteins Involved in Epithelial-Mesenchymal Transition and Tumor Invasion: Studies on TMPRSS4 and TM4SF5

Kim S, Lee JW

The epithelial-mesenchymal transition (EMT) is one mechanism by which cells with mesenchymal features can be generated and is a fundamental event in morphogenesis. Recently, invasion and metastasis of cancer cells...
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E-Cadherin Expression and DNA Ploidy Analysis in Invasive Squamous Cell Carcinoma of the Uterine Cervix Comparison with those of CIN

Kim YJ, Sol MY, Huh MH, Lee SK

  • KMID: 1725271
  • Korean J Pathol.
  • 1997 Jun;31(6):557-565.
Epithelial cadherin (E-cadherin) is a Ca2+ -dependent cell-cell adhesion molecule that connects cells via homotypic interactions. Its function is critical in the induction and maintenance of cell polarity and differentiation,...
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Role of the Epithelial-Mesenchymal Transition in Bladder Cancer: From Prognosis to Therapeutic Target

Yun SJ, Kim WJ

  • KMID: 2315980
  • Korean J Urol.
  • 2013 Oct;54(10):645-650.
Bladder cancer (BC) is the second most common malignancy of urological organs. However, patients with non-muscle-invasive BC are at high risk of recurrence and progression into muscle-invasive BC, and the...
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Lethal Giant Larvae2 Expression Is Reduced or Localized at Cytoplasm in Colon Adenomas and Adenocarcinomas

Jang TJ

  • KMID: 2277557
  • Korean J Pathol.
  • 2010 Oct;44(5):488-492.
BACKGROUND: The Scribble, Par and Crumbs polarity modules are essential for establishing and maintaining apicobasal cell polarity in epithelial cells. The aim of the present study was to investigate the...
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Receptor-specific Ca2+ signaling in polarized cells

Shin DM, Lee MG, Luo X, Muallem S

No abstract available.
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Effects of Wnt-1 on the Growth and Apoptosis of FRTL-5 Cells

Kim JM, Kim TY, Shong YK, Rhee YS, Park EJ, Choi HC, Kim WB

BACKGROUND: Wnt proteins are major signaling molecules involved in embryonic induction, generation of cell polarity and the cell fate decision. A central player in the Wnt signaling pathways is beta-catenin....
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Requirement of Smad4-mediated signaling in odontoblast differentiation and dentin matrix formation

Yun CY, Choi H, You YJ, Yang JY, Baek JA, Cho ES

Dentin is the major part of tooth and formed by odontoblasts. Under the influence of the inner enamel epithelium, odontoblasts differentiate from ectomesenchymal cells of the dental papilla and secrete...
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Reduced Expression of Claudin-7 Correlates with Invasiveness and Nuclear Grade of Breast Carcinomas

Seok SH, Kang SH, Lee SJ, Hwang TY, Bae YK

  • KMID: 1521664
  • Korean J Pathol.
  • 2007 Jun;41(3):158-164.
Background : Claudins are important components of the tight junctions in the intercellular barriers and cell polarity. Among them, claudin-7 is down-regulated in breast cancers compared with the normal breast...
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Calcium-dependent and -independent mechanisms of P2Y receptor regulated anion secretion in polarized epithelia

Wong HY, Ko WH

No abstract available.
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Different uptake of gentamicin through TRPV1 and TRPV4 channels determines cochlear hair cell vulnerability

Lee JH, Park C, Kim SJ, Kim HJ, Oh GS, Shen A, So HS, Park R

  • KMID: 2154231
  • Exp Mol Med.
  • 2013 Mar;45(3):e12.
Hair cells at the base of the cochlea appear to be more susceptible to damage by the aminoglycoside gentamicin than those at the apex. However, the mechanism of base-to-apex gradient...
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Stimulation of Cl- secretion by AlF4- and vanadate in T84 cells

Hwang TH, Jung JS, Bae HR, Yun I, Lee SH

We investigated the mechanism of Cl- secretion by fluoroaluminate(AlF4-) and sodium orthovanadate(vanadate) using the human colonic T84 cell line. T84 cell monolayers grown on collagen-coated filters were mounted in Ussing...
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Acetyl salicylic acid inhibits Th17 airway inflammation via blockade of IL-6 and IL-17 positive feedback

Moon HG, Kang CS, Choi JP, Choi DS, Choi HI, Choi YW, Jeon SG, Yoo JY, Jang MH, Gho YS, Kim YK

  • KMID: 2154224
  • Exp Mol Med.
  • 2013 Jan;45(1):e5.
T-helper (Th)17 cell responses are important for the development of neutrophilic inflammatory disease. Recently, we found that acetyl salicylic acid (ASA) inhibited Th17 airway inflammation in an asthma mouse model...
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