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Mutation analysis of p31(comet) gene, a negative regulator of Mad2, in human hepatocellular carcinoma

Yun MY, Kim SB, Park S, Han CJ, Han YH, Yoon SH, Kim SH, Kim CM, Choi DW, Cho MH, Park GH, Lee KH

  • KMID: 756074
  • Exp Mol Med.
  • 2007 Aug;39(4):508-513.
Failure of mitotic checkpoint machinery leads to the chromosomal missegregation and nuclear endoreduplication, thereby driving the emergence of aneuploidy and tetraploidy population. Although abnormal nuclear ploidy and the resulting impairment...
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