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Effect of Advanced Glycation End Products on Oxidative Stress and Senescence of Trabecular Meshwork Cells

Park CH, Kim JW

PURPOSE: To investigate the effect of advanced glycation end products (AGE) on oxidative stress and cellular senescence in cultured human trabecular meshwork cells (HTMC). METHODS: Primarily cultured HTMC were exposed to...
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Involvement of mitogen-activated protein kinases and p21Waf1 in hydroxyurea-induced G1 arrest and senescence of McA-RH7777 rat hepatoma cell line

Hong SH, Hong BS, Kim DC, Rho MS, Park JI, Rha SH, Jun HS, Jeong JS

  • KMID: 1123771
  • Exp Mol Med.
  • 2004 Oct;36(5):493-498.
Hydroxyurea is commonly used to treat hematologic disorders and some type of solid tumors, but the mechanism for its therapeutic effect is not clearly known. In this study, we examined...
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The effects of laminin on the characteristics and differentiation of neuronal cells from epidermal growth factor-responsive neuroepithelial cells

Park DS, Park JS, Yeon DS

Many extracellular matrix molecules are expressed in the embryonic nervous system and there is some evidence that they are important regulators of neural development. Of these molecules, laminin appears to...
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