- CD99 activates T cells via a costimulatory function that promotes raft association of TCR complex and tyrosine phosphorylation of TCR zeta
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Oh KI, Kim BK, Ban YL, Choi EY, Jung KC, Lee IS, Park SH
- KMID: 1094658
- Exp Mol Med.
- 2007 Apr;39(2):176-184.
We investigated the co-stimulatory role of a cell-surface protein, CD99. Co-ligation of CD99 and suboptimal CD3 induced T-cell activation to a level comparable to that obtained with optimal CD3 or... -
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- Relationship between ganglioside expression and anti-cancer effects of the monoclonal antibody against epithelial cell adhesion molecule in colon cancer
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Kwak DH, Ryu JS, Kim CH, Ko K, Ma JY, Hwang KA, Choo YK
- KMID: 1058707
- Exp Mol Med.
- 2011 Dec;43(12):693-701.
- doi: 10.3858/emm.2011.43.12.080
The human colorectal carcinoma-associated GA733 antigen epithelial cell adhesion molecule (EpCAM) was initially described as a cell surface protein selectively expressed in some myeloid cancers. Gangliosides are sialic acid-containing glycosphingolipids... -
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