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Immunocytochemical Assay of Cathepsin D in Fine Needle Aspiration Cytology of Breast Carcinoma and Benign Breast Diseases

Park K, Ko I

  • KMID: 2013349
  • Korean J Cytopathol.
  • 2000 Dec;11(2):75-81.
Cathepsin D is a protease which is known to facilitate invasion and metastasis of breast carcinoma. Overexpression of cathepsin D is associated with poor clinical outcome and biologic aggressiveness of...
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Cathepsin D Expression in Intestinal Ganglion Cells of Neonate

Kim DY, Lee SC, Park KW, Kim WK

Diagnosing Hirschprung's disease is one of the clinical challenges of this disorder. In the stomach and the intestines, Cathepsin D was readily detected in cytoplasm of the rat gastric and...
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Relationship between Cathepsin D Expression and Other Prognostic Factors in Primary Breast Cancer

Chung WJ, Park DE, Lee KM, Chae KM, Yoon KJ

PURPOSE: Cathepsin D, a lysosomal protease has been proposed to play a role in the local invasion and metastatic dissemination in primary breast cancer. Although there are many conflicting results,...
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Relationship between Cathepsin D Expression and Other Prognostic Factors in Primary Breast Cancer

Chung WJ, Park DE, Lee KM, Chae KM, Yoon KJ

  • KMID: 2324939
  • J Korean Surg Soc.
  • 2001 Apr;60(4):368-374.
PURPOSE: Cathepsin D, a lysosomal protease has been proposed to play a role in the local invasion and metastatic dissemination in primary breast cancer. Although there are many conflicting results,...
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Cathepsin D in Glial Tumors: Comparative Study with PCNA and Cell Cycle Analysis

Chong YG, Han KS, Kim IS, Lee HK, Lee KC, Chu JW

  • KMID: 2187823
  • J Korean Neurosurg Soc.
  • 1993 Feb;22(2):221-228.
No abstract available.
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Analysis of Histopathological Findings of Hirschsprung's Disease: Immunohistochemical Studies Including GDNF and Cathepsin D

Koo H, Choi KJ

No abstract available in English.
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Immunohistochemical Expression of p53 and Cathepsin D in Prostatic Carcinoma

Kim DJ, Kim EH, Yang SH, Kim CJ

  • KMID: 2007099
  • J Korean Cancer Assoc.
  • 2000 Aug;32(4):810-816.
PURPOSE: To evaluate the prognostic significances of p53 and cathepsin D in the prostatic carcinoma, we compared them to other prognostic factors, such as nuclear grade and clinical stage. MATERIALS AND...
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Expression of Chromogranin A, Cathepsin D, Cyclin D1 and p53 proteins in Colorectal Adenocarcinoma

Suh CH, Lee MJ, Cho SK

  • KMID: 2141020
  • Korean J Pathol.
  • 2001 Feb;35(1):7-13.
BACKGROUND: The purpose of this study is to assess the roles of chromogranin A, cathepsin D, cyclin D1 and p53 protein expression in colorectal tumorigenesis. METHODS: 83 colorectal cancer and...
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Prognostic Significance of Cathepsin-D Expression in Breast Cancer

Kwon YT, Jung CJ, Kim YH, Cho SH, Kim SS, Hong SH

  • KMID: 2005561
  • J Korean Surg Soc.
  • 1998 Aug;55(2):176-184.
BACKGROUND: Cathepsin D is an acid optimal protease present in a variety of normal and neoplastic tissues. Cathepsin D is an aspartylendopeptidase which is thought to be important in intracellular...
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The Difference of Cathepsin D Expression between Invasive Ductal Carcinoma and Ductal Carcinoma In Situ of the Breast

Yoon HK, Jung SJ

  • KMID: 2277696
  • Korean J Pathol.
  • 2004 Dec;38(6):408-414.
BACKGROUND: It is known that cathepsin D expression in host stromal cells is associated with a more aggressive tumor behavior in breast cancers. METHODS: Cathepsin D expression was examined in...
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Influence of cathepsin D expression on prognosis in non-small cell lung cancer

Youm HR, Myeong JI, Lim JC, Kim HK, Lee NH, Lee DH, Ko HM, Moon JY, Kang HS, Rheu HS, Kim W, Park CS, Park KO

BACKGROUND: Cathepsin D, an aspartic lysosomal proteinase, is believed to be involved in local invasion and metastasis of tumor cells by its proteolytic activity and has been described to be...
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Tumor Angiogenesis and Cathepsin-D Expression in Invasive Ductal Carcinoma of the Breast

Bae YG, Suh DH, Kim DS, Lee SJ

  • KMID: 2275744
  • Korean J Pathol.
  • 1997 Aug;31(8):735-744.
This study was conducted to assess the prognostic value of tumor angiogenesis and Cathepsin-D in breast carcinoma, by correlating them with other clinicopathologic prognostic factors. In order to estimate microvessels...
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Lysosomal Changes of Retinal Pigment Epithelium

Kim IT, Kwak JS

  • KMID: 1949762
  • J Korean Ophthalmol Soc.
  • 1990 Mar;31(3):309-327.
This study was carried out to investigate diurnal changes of lysosomes includ ing ultrastructural changes of phagosomes and activity of acid phosphatase in the phagosomes and diurnal biochemical changes of...
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Immunohistochemical Analysis of the Expression of Cathepsin D in Human Gastric Adenocarninoma

Han SU, Joo HJ, Cho YK, Lee KP, Kim MW

  • KMID: 1531921
  • J Korean Cancer Assoc.
  • 1997 Feb;29(1):93-102.
PURPOSE: Cathepsin D is an acidic lysosomal proteinase involved in intracellular protein turnover. Increased levels of this enzyme have been reported to be indicators of aggressive tumor behavior in some...
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C-reactive protein, a disintegrin and metalloproteinase 17 protein, and cathepsin D in chronic periodontitis with type 2 diabetes mellitus

Moon KK, Kim HK, Kim YG, Suh JY, Lee JM

The purpose of this study was to compare and quantify the expression of C-reactive protein (CRP), a disintegrin and metalloproteinase 17 (ADAM17) protein, and cathepsin D in the gingival tissues...
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Tumor Angiogenesis and Cathepsin D Expression in Benign, Borderline and Malignant Epithelial Tumors of the Ovary

Park IS, Bae YC

  • KMID: 2143468
  • Korean J Gynecol Oncol Colposc.
  • 2003 Sep;14(3):218-228.
OBJECTIVE: Tumor angiogenesis and proteolysis have a role in tumor invasion and metastasis in various types of tumor. But the prognostic significance in ovarian epithelial tumors has not been established....
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Degradation of phagosomes and diurnal changes of lysosomes in rabbit retinal pigment epithelium

Kim IT, Kwak JS

Diurnal changes of lysosomes including ultrastructural changes of phagosomes and acid phosphatase reactions in phagosomes, as well as diurnal biochemical changes in cathepsin D activity, were studied in the retinal...
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Expression of p53, c-erbB2, bcl-2, Cathepsin D in Infiltrating Ductal Cancer of the Breast

Kang HJ, Kim SW, Yun YK, Oh SK, Choe KJ, Noh DY

PURPOSE: Most treatment decisions for breast cancer patients are based on an assesment of prognostic factors. Tumor markersB (p53, c-erbB2, bcl-2, Cathepsin D) have been evaluated for their prognostic factors...
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Expression of p53, c-erbB2, bcl-2, Cathepsin D in Infiltrating Ductal Cancer of the Breast

Kang HJ, Kim SW, Yun YK, Oh SK, Choe KJ, Noh DY

  • KMID: 2209395
  • J Korean Surg Soc.
  • 2001 Jun;60(6):592-599.
PURPOSE: Most treatment decisions for breast cancer patients are based on an assesment of prognostic factors. Tumor markersB (p53, c-erbB2, bcl-2, Cathepsin D) have been evaluated for their prognostic factors...
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Risk Factors for Lymph-ode Metastasis in Early Gastric Carcinomas

Kim JH, Han SU, Cho YK, Kim MW

  • KMID: 1940176
  • J Korean Surg Soc.
  • 1998 Dec;55(6):818-825.
BACKGROUND: Although regional lymph-ode metastasis from early gastric cancer (EGC) is rare, it is well known that EGC patients with lymph-ode metastasis constitute a high-isk group for recurrence. Thus, it...
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