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Involvement of Sox-4 in the cytochrome c-dependent AIF-independent apoptotic pathway in HeLa cells induced by delta12-prostaglandin J2

Kim BE, Lee JH, Kim HS, Kwon OJ, Jeong SW, Kim IK

  • KMID: 1123765
  • Exp Mol Med.
  • 2004 Oct;36(5):444-453.
delta12-Prostaglandin (PG) J2 is known to elicit an anti-neoplastic effects via apoptosis induction. Previous study showed delta12-PGJ2-induced apoptosis utilized caspase cascade through cytochrome c-dependent pathways in HeLa cells. In this...
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-Melanocyte Stimulating Hormone (MSH) decreases cyclosporine A induced apoptosis in cultured human proximal tubular cells

Jo SK, Lee SY, Han SY, Cha DR, Cho WY, Kim HK, Won NH

The pathogenesis of chronic cyclosporine A (CsA) nephrotoxicity has not been elucidated, but apoptosis is thought to play an important role in CsA induced tubular atrophy. Recently Fas-Fas ligand system...
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