- Prostaglandin A2 Induces Caspase-independent Apoptosis in Hepatocellular Carcinoma Cells
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Kim HS, Shim JC, Choi JY, Rhim H, Kim IK
- KMID: 760582
- Korean J Hepatol.
- 2005 Mar;11(1):72-79.
BACKGROUND/AIMS: Prostaglandin (PG) A2 has been reported to inhibit the growth of hepatocellular carcinoma cells via activation of apoptosis, although the molecular mechanisms involved have not been clarified, yet.... -
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- D4-GDI is cleaved by caspase-3 during daunorubicin-induced apoptosis in HL-60 cells
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Kwon KB, Park EK, Ryu DG, Park BH
- KMID: 1093595
- Exp Mol Med.
- 2002 Mar;34(1):32-37.
Daunorubicin, an anti-cancer drug, is known to induce apoptosis in HL-60 cells in a dose-dependent manner through the activation of caspase-3 (CPP32). Caspase-3 selective inhibitor, Ac-DEVD-CHO, prevented both the activation... -
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- Pseudolaric acid B induces apoptosis via activation of c-Jun N-terminal kinase and caspase-3 in HeLa cells
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Gong X, Wang M, Wu Z, Tashiro SI, Onodera S, Ikejima T
- KMID: 1103322
- Exp Mol Med.
- 2004 Dec;36(6):551-556.
Pseudolaric acid B was isolated from Pseudolarix kaempferi Gordon (Pinaceae) and was evaluated for the anti-cancer effect in HeLa cells. We observed that pseudolaric acid B inhibited cell proliferation and... -
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- Norcantharidin Induces Human Melanoma A375-S2 Cell Apoptosis through Mitochondrial and Caspase Pathways
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An WW, Wang MW, Tashiro SI, Onodera S, Ikejima T
- KMID: 2157686
- J Korean Med Sci.
- 2004 Aug;19(4):560-566.
- doi: 10.3346/jkms.2004.19.4.560
Norcantharidin (NCTD) is the demethylated form of cantharidin, which is the active substance of mylabris. To examine the pathway of NCTD-induced A375-S2 cell death, 3-(4, 5-dimethylthiazol-2-yl)-2, 5-dipheyltetrazolium bromide (MTT) assay,... -
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