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Effect of Hypoxia on the Signal Transduction of Apoptosis in Osteoblasts

Park YJ, Oh ST, Kang KH, Kim SC

  • KMID: 1976475
  • Korean J Orthod.
  • 2003 Dec;33(6):453-463.
Mammalian cell is critically dependent on a continuous supply of oxygen. Even brief periods of oxygen deprivation can result in profound cellular damage. The aim of this study was to...
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Mechanism Underlying Curcumin-induced Apoptosis and Cell Cycle Arrest on SCC25 Human Tongue Squamous Cell Carcinoma Cell Line

Moon JB, Lee KH, Kim IR, Kim GC, Kwak HH, Park BS

  • KMID: 1703488
  • Int J Oral Biol.
  • 2014 Mar;39(1):23-33.
Several studies have shown that curcumin, which is derived from the rhizomes of turmeric, possesses antimicrobial, antioxidant and anti-inflammatory properties. The antitumor properties of curcumin have also now been demonstrated...
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Role of p-38 MAP Kinase in apoptosis of hypoxia-induced osteoblasts

Yoon JH, Jeong AJ, Kang KH, Kim SC

  • KMID: 1976489
  • Korean J Orthod.
  • 2003 Jun;33(3):169-183.
Tooth movement by orthodontic force effects great tissue changes within the periodontium, especially by shifting the blood flow in the pressure side and resulting in a hypoxic state of low...
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Induction of Apoptosis in Human Oral Squamous Carcinoma Cells by Extracellular Products from Pseudomonas aeruginosa

Kim GC, Kang HH, Kim HC, Kim IR, Lee MH, Koo BC, Kim DH, Min JH, Park BS

  • KMID: 1564371
  • Korean J Anat.
  • 2005 Aug;38(4):337-344.
It was reported that cancer in humans and animals infected with microbial pathogens was regressed about 100 years ago. Bacteria are able to trigger apoptosis by a variety of mechanisms...
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Mechanism Underlying NaF-induced Apoptosis and Cell Cycle Arrest on G361 Human Melanoma Cell Line

Kim DK, Sohn HJ, Kim IR, Kim GC, Park BS, Kwak HH

  • KMID: 1449615
  • Korean J Phys Anthropol.
  • 2011 Dec;24(4):203-216.
Fluoride is widely used in dentistry to prevent dental caries, even though the safety of fluoride is a controversial issue. There are no known adverse effects of long-term fluoride ingestion...
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Induction of Apoptosis by Genistein in Human Melanoma Cells

Hur YJ, Gil YG, Baek CJ, Kim IR, Jo UB, Kwak HH, Park BS, Kim GC

  • KMID: 2092947
  • Korean J Anat.
  • 2008 Dec;41(4):233-239.
Genistein is a naturally occurring isoflavone that has been identified predominantly in soybean. It has been found that genistein can inhibit the growth of various cancer cell lines. Melanoma continues...
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Role of p53 and p38 MAPK on Doxorubicin and Lovastatin-induced Apoptosis in Colon Cancer Cells

Park WC, Lee JK, Pak RK

  • KMID: 2209881
  • J Korean Surg Soc.
  • 2003 Oct;65(4):267-278.
PURPOSE: Apoptosis plays a central role in tumor development and it has been hypothesized that lack or failure of apoptosis leads to the development of tumors, including colon cancers. Anticancer...
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zVAD-fmk, unlike BocD-fmk, does not inhibit caspase-6 acting on 14-3-3/Bad pathway in apoptosis of p815 mastocytoma cells

Yee SB, Baek SJ, Park HT, Jeong SH, Jeong JH, Kim TH, Kim JM, Jeong BK, Park BS, Kwon TK, Yoon I, Yoo YH

  • KMID: 1115941
  • Exp Mol Med.
  • 2006 Dec;38(6):634-642.
In a preliminary study, we found that benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone (zVAD- fmk), unlike Boc-aspartyl(OMe)-fluoromethylketone (BocD-fmk), at usual dosage could not prevent genistein-induced apoptosis of p815 mastocytoma cells. This study was undertaken to...
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