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Puromycin aminonucleoside triggers apoptosis in podocytes by inducing endoplasmic reticulum stress

Min SY, Ha DS, Ha TS

BACKGROUND: Puromycin aminonucleoside (PAN) is a known podocytotoxin. PAN-induced nephrosis is a widely used animal model for studying human idiopathic nephrotic syndrome. Abnormal protein accumulation associated with podocyte-specific endoplasmic reticulum...
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