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Are sodium-glucose co-transporter-2 inhibitors associated with improved outcomes in diabetic patients admitted to intensive care units with septic shock?

Ashcherkin N, Abdalla AA, Gupta S, Bhatt S, Yee CI, Cartin-Ceba R

Background: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have been shown to reduce organ dysfunction in renal and cardiovascular disease. There are limited data on the role of SGLT2i in acute organ dysfunction....
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Cytokine profiles in intensive care unit delirium

Smith RJ, Lachner C, Singh VP, Trivedi S, Khatua B, Cartin-Ceba R

Background: Neuroinflammation causing disruption of the blood-brain barrier and immune cell extravasation into the brain parenchyma may cause delirium; however, knowledge of the exact pathophysiologic mechanism remains incomplete. The purpose...
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