- Ectopic expression of cyclooxygenase-2-induced dedifferentiation in articular chondrocytes
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Lee WK, Yu SM, Cheong SW, Sonn JK, Kim SJ
- KMID: 1072952
- Exp Mol Med.
- 2008 Dec;40(6):721-727.
- doi: 10.3858/emm.2008.40.6.721
Cyclooxygenase-2 (COX-2) is known to modulate bone metabolism, including bone formation and resorption. Because cartilage serves as a template for endochondral bone formation and because cartilage development is initiated by... -
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- Transforming growth factor-beta 1 responsiveness of human articular chondrocytes in vitro: normal versus osteoarthritis
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Jahng JS, Lee JW, Han CD, Kim SJ, Yoo NC
- KMID: 699928
- Yonsei Med J.
- 1997 Feb;38(1):40-51.
- doi: 10.3349/ymj.1997.38.1.40
The transforming growth factor-beta 1 was known as having the most important influence on chondrocytes among various growth factors, being abundant in articular chondrocytes and osteocytes. We performed... -
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- The Modulation of Integrin Expression by the Extracellular Matrix in Articular Chondrocytes
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Kim SJ, Kim EJ, Kim YH, Hahn SB, Lee JW
- KMID: 720880
- Yonsei Med J.
- 2003 Jun;44(3):493-501.
- doi: 10.3349/ymj.2003.44.3.493
Normal articular cartilage is composed of chondrocytes embedded within an extracellular matrix (ECM). The patterns of integrin expression determine the adhesive properties of cells by modulating interactions with specific ECMs.... -
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- Withaferin A-Caused Production of Intracellular Reactive Oxygen Species Modulates Apoptosis via PI3K/Akt and JNKinase in Rabbit Articular Chondrocytes
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Yu SM, Kim SJ
- KMID: 2129597
- J Korean Med Sci.
- 2014 Aug;29(8):1042-1053.
- doi: 10.3346/jkms.2014.29.8.1042
Withaferin A (WFA) is known as a constituent of Ayurvedic medicinal plant, Withania somnifera, and has been used for thousands of years. Although WFA has been used for the treatment... -
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