- Synergistic interaction between acetaminophen and L-carnosine improved neuropathic pain via NF-κB pathway and antioxidant properties in chronic constriction injury model
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Owoyele BV, Bakare AO, Olaseinde OF, Ochu MJ, Yusuff AM, Ekebafe F, Fogabi OL, Roi T
- KMID: 2530982
- Korean J Pain.
- 2022 Jul;35(3):271-279.
- doi: 10.3344/kjp.2022.35.3.271
Background: Inflammation is known to underlie the pathogenesis in neuropathic pain. This study investigated the anti-inflammatory and neuroprotective mechanisms involved in antinociceptive effects of co-administration of acetaminophen and L-carnosine in... -
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- Effects of carnosine and hypothermia combination therapy on hypoxic-ischemic brain injury in neonatal rats
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Byun JC, Lee SR, Kim CS
- KMID: 2518886
- Clin Exp Pediatr.
- 2021 Aug;64(8):422-428.
- doi: 10.3345/cep.2020.01837
Background: Carnosine has antioxidative and neuroprotective properties against hypoxic-ischemic (HI) brain injury. Hypothermia is used as a therapeutic tool for HI encephalopathy in newborn infants with perinatal asphyxia. However, the... -
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- L-histidine and L-carnosine exert anti-brain aging effects in D-galactose-induced aged neuronal cells
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Kim Y, Kim Y
- KMID: 2502480
- Nutr Res Pract.
- 2020 Jun;14(3):188-202.
- doi: 10.4162/nrp.2020.14.3.188
BACKGROUND/OBJECTIVES: Brain aging is a major risk factor for severe neurodegenerative diseases. Conversely, L-histidine and L-carnosine are known to exhibit neuroprotective effects. The aim of this study was to examine... -
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- The Neuroprotective Effects of Carnosine in Early Stage of Focal Ischemia Rodent Model
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Park HS, Han KH, Shin JA, Park JH, Song KY, Kim DH
- KMID: 2191076
- J Korean Neurosurg Soc.
- 2014 Mar;55(3):125-130.
- doi: 10.3340/jkns.2014.55.3.125
OBJECTIVE: This study was conducted to elucidate neuroprotective effect of carnosine in early stage of stroke. METHODS: Early stage of rodent stroke model and neuroblastoma chemical hypoxia model was established by... -
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- Biological functions of histidine-dipeptides and metabolic syndrome
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Song BC, Joo NS, Aldini G, Yeum KJ
- KMID: 2313704
- Nutr Res Pract.
- 2014 Feb;8(1):3-10.
The rapid increase in the prevalence of metabolic syndrome, which is associated with a state of elevated systemic oxidative stress and inflammation, is expected to cause future increases in the... -
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- Effects of alpha-lipoic acid and L-carnosine supplementation on antioxidant activities and lipid profiles in rats
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Kim MY, Kim EJ, Kim YN, Choi C, Lee BH
- KMID: 2313547
- Nutr Res Pract.
- 2011 Oct;5(5):421-428.
alpha-Lipoic acid and L-carnosine are powerful antioxidants and are often used as a health supplement and as an ergogenic aid. The objective of this study was to investigate the effects... -
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- Effects of carnosine and related compounds on monosaccharide autoxidation and H2O2 formation
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Lee BJ, Kang KS, Nam SY, Park JH, Lee YS, Yun YW, Cho MH
- KMID: 2285219
- Korean J Physiol Pharmacol.
- 1999 Jun;3(3):251-261.
The effects of carnosine and related compounds (CRCs) including anserine, homocarnosine, histidine, and beta-alanine on monosaccharide autoxidation and H2O2 formation were investigated. The incubation of CRCs with D-glucose, D-glucosamine, and D, L-glyceraldehyde at 37degreeC... -
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