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Enhanced induction of Bax gene expression in H460 and H1299 cells with the combined treatment of cisplatin and adenovirus mediated wt-p53 gene transfer

Choi JH, Ahn KS, Kim JG, Hong YS

  • KMID: 927130
  • Exp Mol Med.
  • 2000 Mar;32(1):23-28.
Cytotoxic effect of either cisplatin or p53 gene transfection of lung cancer cells may be different depending on the p53 status of cells. We investigated cytotoxic effects on the combined...
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The effects of transferring tumor suppressor gene p16INK4A to p16INK4A-deleted cancer cells

Lee KY, Yoo CG, Han SK, Shim YS, Kim YW

  • KMID: 759084
  • Korean J Intern Med.
  • 1999 Jan;14(1):53-58.
OBJECTIVES: p16 is known to be an important tumor suppressor gene and is also called MTS1 (multiple tumor suppressive gene 1). Especially in the case of non-small cell...
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DNA ploidy and proliferative activity in bcl-2 expressed non-small cell lung cancer

Kim YC, Park KO, Kim HJ, Choi IS, Park CS, Juhng SW

  • KMID: 1051550
  • Korean J Intern Med.
  • 1996 Jun;11(2):101-107.
OBJECTIVES: The expressions of bcl-2 have been reported recently in non-small cell lung carcinoma (NSCLC*). As oncogensis is believed to involve a number of genetic alterations, there can be differences...
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The Different Effect of VEGF Polymorphisms on the Prognosis of Non-Small Cell Lung Cancer according to Tumor Histology

Lee S, Kang HG, Choi JE, Lee JH, Kang HJ, Baek SA, Lee E, Seok Y, Lee WK, Lee SY, Yoo SS, Lee J, Cha SI, Kim CH, Cho S, Park JY

Vascular endothelial growth factor (VEGF) contributes to tumor angiogenesis. The role of VEGF single nucleotide polymorphisms (SNPs) in lung cancer susceptibility and its prognosis remains inconclusive and controversial. This study...
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Detection of EGFR and KRAS Mutation by Pyrosequencing Analysis in Cytologic Samples of Non-Small Cell Lung Cancer

Lee SE, Lee SY, Park HK, Oh SY, Kim HJ, Lee KY, Kim WS

EGFR and KRAS mutations are two of the most common mutations that are present in lung cancer. Screening and detecting these mutations are of issue these days, and many different...
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