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Regulation of cell growth by fatty acid-CoA ligase 4 in human hepatocellular carcinoma cells

Sung YK, Park MK, Hong SH, Hwang SY, Kwack MH, Kim JC, Kim MK

  • KMID: 756070
  • Exp Mol Med.
  • 2007 Aug;39(4):477-482.
Fatty acid-CoA ligase 4 (FACL4) is a central enzyme controlling the unesterified free arachidonic acid (AA) level in cells and the free AA is known to induce apoptosis. We have...
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NADPH Oxidase 1 and NADPH Oxidase 4 Have Opposite Prognostic Effects for Patients with Hepatocellular Carcinoma after Hepatectomy

Ha SY, Paik YH, Yang JW, Lee MJ, Bae H, Park CK

BACKGROUND/AIMS: Nicotinamide adenine dinucleotide phosphate oxidase (NOX)-mediated reactive oxygen species contribute to various liver diseases, including hepatocellular carcinoma (HCC). Uncertainties remain regarding the prognostic relevance of NOX1 and NOX4 protein...
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A novel prognostic factor for hepatocellular carcinoma: protein disulfide isomerase

Yu SJ, Won JK, Ryu HS, Choi WM, Cho H, Cho EJ, Lee JH, Kim YJ, Suh KS, Jang JJ, Kim CY, Lee HS, Yoon JH, Cho KH

BACKGROUND/AIMS: Protein disulfide isomerase (PDI) has been implicated in the survival and progression of some cancer cells, by compensating for endoplasmic reticulum stress by upregulating the protein-folding capacity. However, its...
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