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Expression of c-myc and c-Ha-ras oncogens in human colon cancer

Bae OS, Park SD, Kang JS, Suh MH

  • KMID: 1687916
  • J Korean Soc Microbiol.
  • 1991 Aug;26(4):389-393.
No abstract available.
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Inhibition of Carcinogenic Effects of N-Hydroxy-e-acetylaminofluorene by Vitamin Antioxidants

Sung NE, Hong YS

The principal role of cytochrome P-450 in many other mixed function oxidase reactions including hydroxylations or oxidative dealkylations of various drugs, fatty acids, steroids, pesticides, and carcinogens. In order to...
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Formation of 8-hydroxydeoxyguanine moiety in human bladder cellular DNA by bladder carcinogens

Lee SW, Kim SW, Chung MH

  • KMID: 2036794
  • Korean J Urol.
  • 1993 Feb;34(1):16-25.
The 8-hydroxydeoxyguanosine (8-OH-dG), DNA adduct produced by oxygen radical-induced hydroxylation of C-8 position of guanine residue is accepted as to cause mutation and associate with carcinogenesis, and there are many...
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Cytochrome P-450 Dependent Hydroxylation of Chemical Carcinogens

Hong YS

A large number of chemicals have the ability to induce cancer in a variety of tissues of various hosts, including man. Despite current interest in the viral etiology of a...
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Occupational Burden of Cancer in Korea

Kim EA, Lee HE, Kang SK

  • KMID: 2316977
  • Saf Health Work.
  • 2010 Sep;1(1):61-68.
OBJECTIVES: The extent of the occupational cancer burden has rarely been estimated in Korea. The aim of this study is to provide an estimation of the population attributable fraction (PAF)...
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Cytochrome P450 and Cancer

Hong YS

The cytochrome P450(P450) are a large group of constitutive and inducible heme-containing enzymes, which have a central role in the oxidative metabolism of a diverse range of xenobiotics. The majority...
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Concepts of Occupational Exposure Limit and Their International Comparisons

Koh KS, Cho SH

  • KMID: 2141617
  • Korean J Occup Environ Med.
  • 1995 Feb;7(1):152-168.
This paper focuses on the origin of the concepts of occupational exposure limit, and traces the history and development of thoughts and regislations of various countries and organizations concerning the...
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Thyroid Cancer: We Need a Carcinogen-specific Genome Study

Bae JM

No abstract available.
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Scientific rationale and applicability of dose-reponse models for environmental carcinogens

Shin D, Chung Y, Kim J, Lee SG, Hwang M

  • KMID: 2282787
  • Korean J Prev Med.
  • 1996 Mar;29(1):27-42.
This study described methods to predict human health risk associated with exposure to environmental carciongens using animal bioassay data. Also, biological assumption for various dose-response models were reviewed. To illustrate...
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Characteristics of Occupational Lung Cancer from 1999 to 2005

Lim JW, Park SY, Choi BS

  • KMID: 2028504
  • Korean J Occup Environ Med.
  • 2010 Sep;22(3):230-239.
OBJECTIVES: The aim of this study was to investigate the characteristics of occupational lung cancer. METHODS: We analyzed the characteristics of 53 occupational lung cancer cases among 128 lung cancer cases...
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Mouse Models of Gastric Carcinogenesis

Yu S, Yang M, Nam KT

  • KMID: 2372515
  • J Gastric Cancer.
  • 2014 Jun;14(2):67-86.
Gastric cancer is one of the most common cancers in the world. Animal models have been used to elucidate the details of the molecular mechanisms of various cancers. However, most...
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An Overview of Carcinogenic Heavy Metal: Molecular Toxicity Mechanism and Prevention

Kim HS, Kim YJ, Seo YR

Almost all heavy metals are serious toxicants as carcinogens. However, due to their chemical and physiological properties, heavy metals are useful in industrial areas including alloy, smelting and production of...
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CpG Island Hypermethylation in Gastric Carcinoma and Its Premalignant Lesions

Kang GH

Gastric cancers arise through a multistep process characterized by the progressive accumulation of molecular alterations in which genetic and epigenetic mechanisms have been implicated. Gastric cancer is one of the...
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Effect of Several Heavy Metals on the Frequencies of Sister Chromatid Exchanges and Chromosomal Aberrations in Human Lymphocytes

Jung CD, Lee JS, Koh DH, Ki NS, Hwang ID

  • KMID: 2282427
  • Korean J Prev Med.
  • 1989 Mar;22(1):116-124.
To assay the cytogenetic toxicity of NiCl, K2Cr2O7CdC12, and HgC12, the frequencies of sister chromatid exchanges(SCEs) and chromosomal aberrations were observed in the metaphase chromosomes of the human lymphocytes which...
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Exposure Assessment Suggests Exposure to Lung Cancer Carcinogens in a Painter Working in an Automobile Bumper Shop

Kim B, Yoon JH, Choi BS, Shin YC

  • KMID: 2317106
  • Saf Health Work.
  • 2013 Dec;4(4):216-220.
A 46-year-old man who had worked as a bumper spray painter in an automobile body shop for 15 years developed lung cancer. The patient was a nonsmoker with no family...
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Decision Tree of Occupational Lung Cancer Using Classification and Regression Analysis

Kim TW, Koh DH, Park CY

  • KMID: 2316987
  • Saf Health Work.
  • 2010 Dec;1(2):140-148.
OBJECTIVES: Determining the work-relatedness of lung cancer developed through occupational exposures is very difficult. Aims of the present study are to develop a decision tree of occupational lung cancer. METHODS: 153...
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Establishing a Policy Framework for the Primary Prevention of Occupational Cancer: A Proposal Based on a Prospective Health Policy Analysis

Veglia A, Pahwa M, Demers PA

BACKGROUND: Despite our knowledge of the causes of cancer, millions of workers are involuntarily exposed to a wide range of known and suspected carcinogens in the workplace. To address this...
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Sister Chromatid Exchanges in Lymphocytes on Normal Human Blood culture with Mercury chloride or Methylmercury Chloride

Koh DH

  • KMID: 2282201
  • Korean J Prev Med.
  • 1984 Sep;17(1):245-250.
Reciprocal exchanges of DNA in sister chromatids (SCEs) are induced by various carcinogens and mutagens, although the quantitative relationship between the number of mutations and SCEs induced varies among chemicals....
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Cardiovascular Disease, Cancer and Reproductive Hazards in Firefighters

Han AR, Linton JA

Firefighters are facing occupational hazards such as exposures to a variety of carcinogens and toxic agents, heat, physical stress and psychological stress. This occupation involves an increased risk of particular...
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Passive Smoking and Lung Cancer

Hwang BB

Active smoking is a major cause of lung cancer. The dose-response relation between exposure to tobacco smoke and risk of lung cancer is almost linear. No threshold level is apparent...
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