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Regulation of Tumor Necrosis Factor-alpha-induced Airway Mucin Production and Gene Expression by Carbenoxolone, Prunetin, and Silibinin

Lee HJ, Lee SY, Jeon BK, Lee JW, Lee MN, Kim JO, Lee CJ

  • KMID: 2319442
  • Tuberc Respir Dis.
  • 2010 Nov;69(5):348-353.
BACKGROUND: In this study, we tried to investigate whether carbenoxolone, prunetin, and silibinin affect tumor necrosis factor (TNF)-alpha-induced MUC5AC mucin production and gene expression from human airway epithelial cells. METHODS: Confluent...
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Influence of Sex on Gap Junctional Distribution and Vascular Dilatation in the Rat Mesenteric Arteries

Han SS, Bahk JH, Huh J

BACKGROUND: Besides prostacyclin and nitric oxide, the endothelium-derived hyperpolarizing factor (EDHF), which is another distinct endothelium-dependent vasodilator, is involved in relaxing the vascular smooth muscle cells. The myoendothelial gap junction...
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Influence of Myoendothelial Gap Junction on the Regulation of Vasomotor Tone

Huh J, Ro YJ, Min SW, Kim CS, Kang SS, Jung IY, Park WS, Chung SH, Bahk JH

BACKGROUND: In addition to nitric oxide (NO) and prostacyclin (PGI2), there is another endothelium-derived mechanism of smooth muscle relaxation, which is associated with an endothelium-derived hyperpolarizing factor (EDHF). To assess...
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