- Gut-derived lipopolysaccharide promotes alcoholic hepatosteatosis and subsequent hepatocellular carcinoma by stimulating neutrophil extracellular traps through toll-like receptor 4
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Liu Y, Zhang X, Chen S, Wang J, Yu S, Li Y, Xu M, Aboubacar H, Li J, Shan T, Wang J, Cao G
- KMID: 2531376
- Clin Mol Hepatol.
- 2022 Jul;28(3):522-539.
- doi: 10.3350/cmh.2022.0039
Background/Aims: Binge drinking leads to many disorders, including alcoholic hepatosteatosis, which is characterized by intrahepatic neutrophil infiltration and increases the risk of hepatocellular carcinoma (HCC). Molecular mechanisms may involve the... -
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- CXCL-13 Regulates Resistance to 5-Fluorouracil in Colorectal Cancer
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Zhang G, Luo X, Zhang W, Chen E, Xu J, Wang F, Cao G, Ju Z, Jin D, Huang X, Zhou W, Song Z
- KMID: 2500346
- Cancer Res Treat.
- 2020 Apr;52(2):622-633.
- doi: 10.4143/crt.2019.593
Purpose 5-Fluorouracil (5-Fu) is used as a conventional chemotherapy drug in chemotherapy for patients with advanced colorectal cancer, but many patients still suffer from treatment failure due to 5-Fu resistance. Emerging observations revealed... -
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