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The Cannabinoid Agonist WIN55,212-2 Suppresses Opioid-induced Pruritus in Mice

Lee H

  • KMID: 2263295
  • Anesth Pain Med.
  • 2008 Jul;3(3):167-171.
BACKGROUND: Cannabinoid receptor agonists can reverse opioidinduced nausea and vomiting in animals, but have not yet been tested against opioid-induced pruritus. This study tests the hypothesis that a cannabinoid receptor...
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Selective Cannabinoid Receptor-1 Agonists Regulate Mast Cell Activation in an Oxazolone-Induced Atopic Dermatitis Model

Nam G, Jeong SK, Park BM, Lee SH, Kim HJ, Hong SP, Kim B, Kim BW

BACKGROUND: Many inflammatory mediators, including various cytokines (e.g. interleukins and tumor necrosis factor [TNF]), inflammatory proteases, and histamine are released following mast cell activation. However, the endogenous modulators for mast...
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Assessment of the Abuse Liability of Synthetic Cannabinoid Agonists JWH-030, JWH-175, and JWH-176

Tampus R, Yoon SS, de la Pena JB, Botanas CJ, Kim HJ, Seo JW, Jeong EJ, Jang CG, Cheong JH

The emergence and use of synthetic cannabinoids have greatly increased in recent years. These substances are easily dispensed over the internet and on the streets. Some synthetic cannabinoids were shown...
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Fluoroscopic Characterization of Colonic Dysmotility Associated to Opioid and Cannabinoid Agonists in Conscious Rats

Díaz-Ruano S, López-Pérez AE, Girón R, Pérez-García I, Martín-Fontelles MI, Abalo R

  • KMID: 2449102
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):300-315.
  • doi: 10.5056/jnm18202
BACKGROUND/AIMS: Gastrointestinal adverse effects have a major impact on health and quality of life in analgesics users. Non-invasive methods to study gastrointestinal motility are of high interest. Fluoroscopy has been...
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