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Glioma Stem Cell-Targeted Dendritic Cells as a Tumor Vaccine Against Malignant Glioma

Ji B, Chen Q, Liu B, Wu L, Tian D, Guo Z, Yi W

PURPOSE: Cancer stem cells have recently been thought to be closely related to tumor development and reoccurrence. It may be a promising way to cure malignant glioma by using glioma...
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Activated natural killer cell-mediated immunity is required for the inhibition of tumor metastasis by dendritic cell vaccination

Kim A, Noh YW, Kim KD, Jang YS, Choe YK, Lim JS

  • KMID: 1123764
  • Exp Mol Med.
  • 2004 Oct;36(5):428-443.
Immunization with dendritic cells (DCs) pulsed with tumor antigen can activate tumor-specific cytotoxic T lymphocytes (CTL), which is responsible for tumor protection and regression. In this study, we examined whether...
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Biologic Therapy for Brain Cancers - Based on Cellular and Immunobiology

Okada H

The overall goal of our research projects is to develop effective immunotherapeutic regimens, particularly combining vaccine and gene therapy/ cell therapy strategies. For the development of clinically effective immunotherapy for...
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