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Tables of Contents (Vol. 56, No. 1~4, 2024)

  • KMID: 2560262
  • Cancer Res Treat.
  • 2024 Oct;56(4):1288-1298.
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Acknowledgment of Reviewers (2024)

  • KMID: 2560263
  • Cancer Res Treat.
  • 2024 Oct;56(4):1299-1303.
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Data Resource Profile: The Cancer Public Library Database in South Korea

Choi DW, Guk MY, Kim HR, Ryu KS, Kong HJ, Cha HS, Kim HJ, Chae H, Jeon YS, Kim H, Jung J, Im JS, Choi KS

This paper provides a comprehensive overview of the Cancer Public Library Database (CPLD), established under the Korean Clinical Data Utilization for Research Excellence project (K-CURE). The CPLD links data from...
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Safe Utilization and Sharing of Genomic Data: Amendment to the Health and Medical Data Utilization Guidelines of South Korea

Park H, Park J, Woo HG, Yun H, Lee M, Hong D

Purpose In 2024, medical researchers in the Republic of Korea were invited to amend the health and medical data utilization guidelines (Government Publications Registration Number: 11-1352000-0052828-14). This study aimed to...
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Effector Function Characteristics of Exhausted CD8+ T-Cell in Microsatellite Stable and Unstable Gastric Cancer

Han DS, Kwak Y, Lee S, Nam SK, Kong SH, Park DJ, Lee HJ, Kwon NJ, Lee HS, Yang HK

Purpose Gastric cancer exhibits molecular heterogeneity, with the microsatellite instability–high (MSI-H) subtype drawing attention for its distinct features. Despite a higher survival rate, MSI-H gastric cancer lack significant benefits from...
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Development and Feasibility Evaluation of Smart Cancer Care 2.0 Based on Patient-Reported Outcomes for Post-Discharge Management of Patients with Cancer

Kwon JA, Yang S, Koh SJ, Noh YJ, Kang DY, Yang SB, Kwon EJ, Seo JW, Kim Js, Ock M

Purpose A “Smart Cancer Care” platform that integrates patient-reported outcomes (PROs) with management has been established in Korea. This study focused on improving health behaviors and connecting patients to welfare...
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Recent Advances in Genomic Approaches for the Detection of Homologous Recombination Deficiency

Kim YN, Gulhan DC, Jin H, Glodzik D, Park PJ

Accurate detection of homologous recombination deficiency (HRD) in cancer patients is paramount in clinical applications, as HRD confers sensitivity to poly(ADP-ribose) polymerase (PARP) inhibitors. With the advances in genome sequencing...
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Longitudinal Comparative Analysis of Circulating Tumor DNA and Matched Tumor Tissue DNA in Patients with Metastatic Colorectal Cancer Receiving Palliative First-Line Systemic Anti-Cancer Therapy

Lee Sb, Kim JW, Kim HG, Hwang SH, Kim KJ, Lee JH, Seo J, Kang M, Jung EH, Suh KJ, Kim SH, Kim JW, Kim YJ, Kim JH, Kwon NJ, Lee KW

Purpose This study aimed to compare tumor tissue DNA (ttDNA) and circulating tumor DNA (ctDNA) to explore the clinical applicability of ctDNA and to better understand clonal evolution in patients...
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Identification of New Pathogenic Variants of Hereditary Diffuse Gastric Cancer

Oh SY, Jang G, Kim J, Jeong KY, Kim HM, Kwak YJ, Kong SH, Park DJ, Lee HJ, Cho SY, Kim JI, Yang HK

Purpose Hereditary diffuse gastric cancer (HDGC) presents a significant genetic predisposition, notably linked to mutations in the CDH1 and CTNNA1. However, the genetic basis for over half of HDGC cases...
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Clinical Outcomes of Surgery after Neoadjuvant Chemotherapy in Locally Advanced Pancreatic Ductal Adenocarcinoma

Lee YN, Sung MK, Hwang DW, Park Y, Kwak BJ, Lee W, Song KB, Lee JH, Yoo C, Kim KP, Chang HM, Ryoo BY, Kim SC

Purpose Clinical outcomes of surgery after neoadjuvant chemotherapy have not been investigated for locally advanced pancreatic cancer (LAPC), despite well-established outcomes in borderline resectable pancreatic cancer (BRPC). This study aimed...
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Combination of Dabrafenib and Trametinib in Patients with Metastatic BRAFV600E-Mutated Thyroid Cancer

Jeon Y, Park S, Lee SH, Kim TH, Kim SW, Ahn MJ, Jung HA, Chung JH

Purpose BRAF mutations are detected in 30%-80% of papillary thyroid cancer (PTC) cases. DaBRAFenib and trametinib showed promising antitumor activity in patients with BRAFV600E-mutated metastatic melanoma and non–small cell lung...
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Prognostic Significance of Bulky Nodal Disease in Anal Cancer Management: A Multi-institutional Study

Chun SJ, Kim E, Jang WI, Kim MS, Kang HC, Kim BH, Chie EK

Purpose This study aimed to assess the prognostic significance of bulky nodal involvement in patients with anal squamous cell carcinoma treated with definitive chemoradiotherapy. Materials and Methods We retrospectively analyzed medical...
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Development of a Prediction Model for Delirium in Hospitalized Patients with Advanced Cancer

Jung EH, Yoo SH, Lee SW, Kang B, Kim YJ

Purpose Delirium is a common neurocognitive disorder in patients with advanced cancer and is associated with poor clinical outcomes. As a potentially reversible phenomenon, early recognition of delirium by identifying...
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Association between Endoscopist Volume and Interval Cancers after Colonoscopy: Results from the National Colorectal Cancer Screening Program in Korea

Kim DJ, Yoon NH, Jun JK, Suh M, Lee S, Kim S, Kim JE, Lee H

Purpose The rate of interval colorectal cancer (iCRC) is now accepted as a key performance indicator of organized colorectal cancer (CRC) screening programs. We aimed to examine the association between...
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A 10-Gene Signature to Predict the Prognosis of Early-Stage Triple-Negative Breast Cancer

Kim CM, Park KH, Yu YS, Kim JW, Park JY, Park K, Yu JH, Lee JE, Sim SH, Seo BK, Kim JK, Lee ES, Park YH, Kong SY

Purpose Triple-negative breast cancer (TNBC) is a particularly challenging subtype of breast cancer, with a poorer prognosis compared to other subtypes. Unfortunately, unlike luminal-type cancers, there is no validated biomarker...
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Varlitinib and Paclitaxel for EGFR/HER2 Co-expressing Advanced Gastric Cancer: A Multicenter Phase Ib/II Study (K-MASTER-13)

Koo DH, Jung M, Kim YH, Jeung HC, Zang DY, Bae WK, Kim H, Kim HS, Lee Ck, Kwon WS, Chung HC, Rha SY

Purpose Varlitinib is a pan-human epidermal growth factor receptor (HER) inhibitor targeting epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and HER4. We present a phase...
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Dural Metastasis in Breast Cancer: MRI-Based Morphological Subtypes and Their Clinical Implications

Ahn SJ, Joo B, Park M, Park HH, Suh SH, Ahn SG, Yoo J

Purpose This study aimed to investigate the clinical factors associated with breast cancer (BRCA) dural metastases (DMs), their impact on prognosis compared to brain parenchymal metastases (BPMs) alone, and differences...
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The Impact of Infectious Mononucleosis History on the Risk of Developing Lymphoma and Nasopharyngeal Carcinoma: A Retrospective Large-Scale Cohort Study Using National Health Insurance Data in South Korea

Kang SH, Lee YH, Myong JP, Kwon M

Purpose This study aimed to assess the long-term risks associated with a history of infectious mononucleosis (IM), primarily caused by the Epstein-Barr virus (EBV). Specifically analyzing the potential increase in...
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Analysis of Response and Progression Patterns of Tyrosine Kinase Inhibitors in Recurrent or Metastatic Adenoid Cystic Carcinoma: A Post Hoc Analysis of Two KCSG Phase II Trials

Kim Y, Keam B, Kang EJ, Kim JS, Kim HR, Lee KW, Kwon JH, Lee KE, Yang Y, Choi YH, Kim MK, Ji JH, Yun T, Choi MY, Lee KH, Kim SB, Ahn MJ

Purpose In this study, we evaluated 66 patients diagnosed with adenoid cystic carcinoma (ACC) enrolled in two Korean Cancer Study Group trials to investigate the response and progression patterns in...
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Clinical and Radiologic Predictors of Response to Atezolizumab-Bevacizumab in Advanced Hepatocellular Carcinoma

Choi SJ, Chung SW, Choi J, Kim KM, Kim HD, Yoo C, Ryoo BY, Lee SS, Choi WM, Choi SH

Purpose This study aimed to identify clinical and radiologic characteristics that could predict response to atezolizumab-bevacizumab combination therapy in patients with advanced hepatocellular carcinoma (HCC). Materials and Methods This single-center retrospective...
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