- Right Then, Wrong Now: Early-Onset Colorectal Cancer in Korea
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Shin A, Jung KW, Jeong SY
- KMID: 2544186
- Cancer Res Treat.
- 2023 Jul;55(3):1058-1060.
- doi: 10.4143/crt.2022.1612
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- Cellular Dormancy in Cancer: Mechanisms and Potential Targeting Strategies
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Min HY, Lee HY
- KMID: 2544156
- Cancer Res Treat.
- 2023 Jul;55(3):720-736.
- doi: 10.4143/crt.2023.468
Cancer is a leading cause of disease-related mortality worldwide. Drug resistance is one of the primary reasons for the failure of anticancer therapy. There are a number of underlying mechanisms... -
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- Efficacy of Olaparib in Treatment-Refractory, Metastatic Breast Cancer with Uncommon Somatic BRCA Mutations Detected in Circulating Tumor DNA
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Yoon JK, Ahn J, Kim S, Kim HP, Kang Jk, Bang D, Lim Y, Kim TY
- KMID: 2544184
- Cancer Res Treat.
- 2023 Jul;55(3):1048-1052.
- doi: 10.4143/crt.2022.1529
Poly(ADP-ribose) polymerase inhibitors have been shown dramatic responses in patients with BRCAness. However, clinical studies have been limited to breast cancer patients with germline mutations. Here, we describe a patient... -
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- Gonadal Function in Female Adolescent and Young Adult Survivors of Childhood Cancer
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Jin HY, Lee JA, Park M, Park HJ
- KMID: 2544179
- Cancer Res Treat.
- 2023 Jul;55(3):992-1000.
- doi: 10.4143/crt.2022.1518
Purpose Childhood cancer survivors (CCSs) are at risk for premature ovarian insufficiency (POI). The aim of this study is to evaluate ovarian function and associated health outcomes in female adolescent... -
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- ERRATUM: Recommendations for the Use of Next-Generation Sequencing and the Molecular Tumor Board for Patients with Advanced Cancer: A Report from KSMO and KCSG Precision Medicine Networking Group
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Yoon S, Kim M, Hong YS, Kim HS, Kim ST, Kim J, Yun H, Yoo C, Ahn HK, Kim HS, Lee IH, Kim IH, Park I, Jeong JH, Cheon J, Kim JW, Yun J, Lim SM, Cha Y, Jang SJ, Zang DY, Kim TW, Kang JH, Kim JH
- KMID: 2544187
- Cancer Res Treat.
- 2023 Jul;55(3):1061-1061.
- doi: 10.4143/crt.2021.1115.E
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- Overview of the National Cancer Screening Program for Colorectal Cancer in Korea over 14 Years (2004-2017)
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Park B, Her EY, Lee K, Nari F, Jun JK, Choi KS, Suh M
- KMID: 2544171
- Cancer Res Treat.
- 2023 Jul;55(3):910-917.
- doi: 10.4143/crt.2022.1432
Purpose This study aimed to evaluate the participation and follow-up test compliance rates and key performance indicators of the National Cancer Screening Program (NCSP) for colorectal cancer (CRC) from 2004... -
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- Genomic Characteristics and the Potential Clinical Implications in Oligometastatic Non–Small Cell Lung Cancer
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Liao R, Chen K, Li J, He H, Yi G, Huang M, Chen R, Shen L, Zhang X, Xu Z, Yang Z, Peng Y
- KMID: 2544163
- Cancer Res Treat.
- 2023 Jul;55(3):814-831.
- doi: 10.4143/crt.2022.1315
Purpose Oligometastatic non–small cell lung cancer (NSCLC) patients have been increasingly regarded as a distinct group that could benefit from local treatment to achieve a better clinical outcome. However, current... -
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- Anti–PD-L1 Antibody and/or 17β-Estradiol Treatment Induces Changes in the Gut Microbiome in MC38 Colon Tumor Model
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Song CH, Kim N, Nam RH, Choi SI, Jang JY, Choi J, Lee HN
- KMID: 2544170
- Cancer Res Treat.
- 2023 Jul;55(3):894-909.
- doi: 10.4143/crt.2022.1427
Purpose 17β-Estradiol (E2) supplementation suppresses MC38 tumor growth by downregulating the expression of programmed death-ligand 1 (PD-L1). This study aims to figure out the gut microbiota that respond to anti–PD-L1... -
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- Circulating Tumor DNA Dynamics and Treatment Outcome of Regorafenib in Metastatic Colorectal Cancer
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Lee DW, Lim Y, Kim HP, Kim SY, Roh H, Kang JK, Lee K, Kim MJ, Ryoo SB, Park JW, Jeong SY, Park KJ, Kang GH, Han SW, Kim TY
- KMID: 2544173
- Cancer Res Treat.
- 2023 Jul;55(3):927-938.
- doi: 10.4143/crt.2023.268
Purpose Circulating tumor DNA (ctDNA) is emerging as a valuable non-invasive tool to identify tumor heterogeneity and tumor burden. This study investigated ctDNA dynamics in metastatic colorectal cancer patients treated... -
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- A Randomized Phase II Study of Irinotecan Plus Cisplatin with or without Simvastatin in Ever-Smokers with Extended Disease Small Cell Lung Cancer
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Lee Y, Lee SH, Lee GK, Lim EJ, Han JY
- KMID: 2544169
- Cancer Res Treat.
- 2023 Jul;55(3):885-893.
- doi: 10.4143/crt.2023.283
Purpose This study evaluated whether an addition of simvastatin to chemotherapy improves survival in ever-smokers with extensive disease (ED)–small cell lung cancer (SCLC). Materials and Methods This is an open-label randomized... -
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- Clinicopathological Analysis and Treatment of Adult Patients with Inflammatory Myofibroblastic Tumor: A 15-Year Single- Center Study
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Liu X, Gong C, Zhang J, Feng W, Guo Y, Sang Y, Wang C, Chen Y, Wang J, Yu L, Zhang X, Luo Z
- KMID: 2544180
- Cancer Res Treat.
- 2023 Jul;55(3):1001-1010.
- doi: 10.4143/crt.2022.894
Purpose Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal malignancy that occurs primarily in children and adolescents. The clinical and pathological features of IMT in adult patients are not well... -
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- MLL4 Regulates the Progression of Non–Small-Cell Lung Cancer by Regulating the PI3K/AKT/SOX2 Axis
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Yang Y, Qiu R, Weng Q, Xu Z, Song J, Zhao S, Meng M, Zhang D, Kong C, Wang H, Xu M, Zhao Z, Ji J
- KMID: 2544161
- Cancer Res Treat.
- 2023 Jul;55(3):778-803.
- doi: 10.4143/crt.2022.1042
Purpose Mixed-lineage leukemia protein 4 (MLL4/KMT2D) is a histone methyltransferase, and its mutation has been reported to be associated with a poor prognosis in many cancers, including lung cancer. We... -
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- The Incidence and Risk Factors of Chronic Pulmonary Infection after Radiotherapy in Patients with Lung Cancer
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Choi Y, Noh JM, Shin SH, Lee K, Um SW, Kim H, Pyo H, Ahn YC, Jeong BH
- KMID: 2544162
- Cancer Res Treat.
- 2023 Jul;55(3):804-813.
- doi: 10.4143/crt.2022.1305
Purpose This study aimed to investigate cumulative incidence and risk factors associated with chronic pulmonary infection (CPI) development after radiotherapy for lung cancer. Materials and Methods We retrospectively analyzed 1,872 patients... -
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- Combination of the LARS1 Inhibitor, BC-LI-0186 with a MEK1/2 Inhibitor Enhances the Anti-Tumor Effect in Non–Small Cell Lung Cancer
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Lee SH, Kim EY, Han JM, Han G, Chang YS
- KMID: 2544166
- Cancer Res Treat.
- 2023 Jul;55(3):851-864.
- doi: 10.4143/crt.2022.1527
Purpose The mammalian target of rapamycin complex 1 (mTORC1) regulates cell growth and proliferation by growth factor coordination and amino acid availability. Leucyl-tRNA synthetase 1 (LARS1) senses the intracellular leucine... -
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- Intraindividual Comparison of MRIs with Extracellular and Hepatobiliary Contrast Agents for the Noninvasive Diagnosis of Hepatocellular Carcinoma Using the Korean Liver Cancer Association–National Cancer Center 2022 Criteria
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Yoon JK, Han DH, Lee S, Choi JY, Choi GH, Kim DY, Kim MJ
- KMID: 2544174
- Cancer Res Treat.
- 2023 Jul;55(3):939-947.
- doi: 10.4143/crt.2022.1645
Purpose The aim of the present study was to evaluate the per-lesion sensitivity and specificity of the Korean Liver Cancer Association–National Cancer Center (KLCA-NCC) 2022 criteria for the noninvasive diagnosis... -
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- Predictors of Post-chemoradiotherapy Pulmonary Complication in Locally Advanced Non–Small Cell Lung Cancer
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Lee TH, Kang BH, Kim HJ, Wu HG, Lee JH
- KMID: 2544167
- Cancer Res Treat.
- 2023 Jul;55(3):865-874.
- doi: 10.4143/crt.2022.1538
Purpose We investigated the clinical effects and predictive factors of severe post-chemoradiotherapy pulmonary complications (PCPC) in locally advanced non–small cell lung cancer (LA-NSCLC). Materials and Methods Medical records of 317 patients... -
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- Eflapegrastim versus Pegfilgrastim for Chemotherapy-Induced Neutropenia in Korean and Asian Patients with Early Breast Cancer: Results from the Two Phase III ADVANCE and RECOVER Studies
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Moon YW, Kim SK, Lee KS, Lee MH, Park YH, Park KH, Kim GM, Lim S, Lee SA, Choi JD, Baek E, Han H, Baek S, Im SA
- KMID: 2544160
- Cancer Res Treat.
- 2023 Jul;55(3):766-777.
- doi: 10.4143/crt.2022.987
Purpose We investigated the consistent efficacy and safety of eflapegrastim, a novel long-acting granulocyte-colony stimulating factor (G-CSF), in Koreans and Asians compared with the pooled population of two global phase... -
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- Early Plasma Circulating Tumor DNA as a Potential Biomarker of Disease Recurrence in Non-metastatic Prostate Cancer
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Fei X, Du X, Gong Y, Liu J, Fan L, Wang J, Wang Y, Zhu Y, Pan J, Dong B, Xue W
- KMID: 2544177
- Cancer Res Treat.
- 2023 Jul;55(3):969-977.
- doi: 10.4143/crt.2022.1557
Purpose In non-metastatic prostate cancer (nmPCa) setting, it is important to early identify the patients at risk of biochemical recurrence (BCR) for immediate postoperative intervention. Our study aimed to evaluate... -
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- Diagnostic Performance of Endosonography to Detect Mediastinal Lymph Node Metastasis in Patients with Radiological N1 Non–Small Cell Lung Cancer
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Kim BG, Cho JH, Shin SH, Lee K, Um SW, Kim H, Kim J, Shim YM, Jeong BH
- KMID: 2544164
- Cancer Res Treat.
- 2023 Jul;55(3):832-840.
- doi: 10.4143/crt.2022.1428
Purpose Guidelines recommend that non–small cell lung cancer (NSCLC) patients with suspected hilar lymph node (LN) metastases should undergo invasive mediastinal LN staging prior to surgical treatment via endosonography. We... -
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- One-Week versus Two-Week Chemoradiotherapy Followed by Curative Surgery in Rectal Cancer: Long-Term Comparative Pooled Analysis of Two Prospective Multicenter Phase II Trials
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Sung SY, Kim DY, Jang HS, Kim TH, Park HC, Chie EK, Nam TK, Kim SH, Lee JH
- KMID: 2544172
- Cancer Res Treat.
- 2023 Jul;55(3):918-926.
- doi: 10.4143/crt.2022.1646
Purpose The optimal short-course chemotherapeutic regimen for rectal cancer has not been clearly defined until now. KROG 10-01 and KROG 11-02 prospective trials investigated the efficacy and safety of 1-... -
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