- Tables of Contents (Vol. 52, No. 1~4, 2020)
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- KMID: 2507956
- Cancer Res Treat.
- 2020 Oct;52(4):1297-1305.
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- Acknowledgment of Reviewers (2020)
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- KMID: 2507957
- Cancer Res Treat.
- 2020 Oct;52(4):1306-1309.
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- The Fear of Cancer from the Standpoint of Oneself, the Opposite Sex and the Fear of Side Effects of Cancer Treatment
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Park K, Kim Y, Yang HK, Min HS
- KMID: 2507926
- Cancer Res Treat.
- 2020 Oct;52(4):993-1001.
- doi: 10.4143/crt.2020.285
Purpose It is important to understand the differences between men and women when it comes to attitudes and risk perception toward disease. This study aimed to explore the fear of... -
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- Crohn’s Disease Following Rituximab Treatment for Follicular Lymphoma in a Patient with Synchronous Gastric Signet Ring Cells Carcinoma: A Case Report and Literature Review
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Cavalcanti E, Armentano R, Lolli I
- KMID: 2507955
- Cancer Res Treat.
- 2020 Oct;52(4):1291-1295.
- doi: 10.4143/crt.2020.406
Recently, there have been a few reports of rituximab (RTX)-induced Crohn’s disease, but there is no literature available on successful long-term treatment and the clinical outcome of this condition. We... -
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- EGFR C797S as a Resistance Mechanism of Lazertinib in Non-small Cell Lung Cancer with EGFR T790M Mutation
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Park S, Ku BM, Jung HA, Sun JM, Ahn JS, Lee SH, Park K, Ahn MJ
- KMID: 2507954
- Cancer Res Treat.
- 2020 Oct;52(4):1288-1290.
- doi: 10.4143/crt.2020.278
The non-small cell lung cancer with activating epidermal growth factor receptor (EGFR) mutation eventually acquires resistant to either first or second-generation EGFR tyrosine kinase inhibitor (TKI). As the following option,... -
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- Cause of Mortality after Radical Prostatectomy and the Impact of Comorbidity in Men with Prostate Cancer: A Multi-institutional Study in Korea
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Pak S, You D, Jeong IG, Lee DE, Kim SH, Joung JY, Lee KH, Hong JH, Kim CS, Ahn H
- KMID: 2507949
- Cancer Res Treat.
- 2020 Oct;52(4):1242-1250.
- doi: 10.4143/crt.2020.286
Purpose This study aimed to examine the causes of death in Korean patients who underwent radical prostatectomy for prostate cancer and investigate the relationship between comorbidity and mortality. Materials and Methods We conducted... -
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- A Multi-cohort Study of the Prognostic Significance of Microsatellite Instability or Mismatch Repair Status after Recurrence of Resectable Gastric Cancer
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An JY, Choi YY, Lee J, Hyung WJ, Kim KM, Noh SH, Choi MG, Cheong JH
- KMID: 2507941
- Cancer Res Treat.
- 2020 Oct;52(4):1153-1161.
- doi: 10.4143/crt.2020.173
Purpose High microsatellite instability (MSI) is related to good prognosis in gastric cancer. We aimed to identify the prognostic factors of patients with recurrent gastric cancer and investigate the role of... -
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- Genetic Alterations in Preinvasive Lung Synchronous Lesions
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Ahn S, Lim J, Park SY, Kim H, Kwon HJ, Han YB, Lee CT, Cho S, Chung JH
- KMID: 2507938
- Cancer Res Treat.
- 2020 Oct;52(4):1120-1134.
- doi: 10.4143/crt.2020.307
Purpose Despite advances in treatment, lung cancer remains the leading cause of cancer mortality. This study aimed to characterise genome-wide tumorigenesis events and to understand the hypothesis of the multistep carcinogenesis... -
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- Elevated Expression of RIOK1 Is Correlated with Breast Cancer Hormone Receptor Status and Promotes Cancer Progression
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Huang Z, Li X, Xie T, Gu C, Ni K, Yin Q, Cao X, Zhang C
- KMID: 2507934
- Cancer Res Treat.
- 2020 Oct;52(4):1067-1083.
- doi: 10.4143/crt.2020.187
Purpose RIOK1 has been proved to play an important role in cancer cell proliferation and migration in various types of cancers—such as colorectal and gastric cancers. However, the expression of RIOK1... -
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- Germline and Somatic BRCA1/2 Gene Mutational Status and Clinical Outcomes in Epithelial Peritoneal, Ovarian, and Fallopian Tube Cancer: Over a Decade of Experience in a Single Institution in Korea
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Kim SI, Lee M, Kim HS, Chung HH, Kim JW, Park NH, Song YS
- KMID: 2507948
- Cancer Res Treat.
- 2020 Oct;52(4):1229-1241.
- doi: 10.4143/crt.2020.557
Purpose This study aimed to present a single institutional experience with BRCA1/2 gene tests and the effects of pathogenic mutations in epithelial peritoneal, ovarian, and fallopian tube cancer (POFTC) on survival... -
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- Adjuvant Chemotherapy in Microsatellite Instability–High Gastric Cancer
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Kim JW, Cho SY, Chae J, Kim JW, Kim TY, Lee KW, Oh DY, Bang YJ, Im SA
- KMID: 2507943
- Cancer Res Treat.
- 2020 Oct;52(4):1178-1187.
- doi: 10.4143/crt.2020.313
Purpose Microsatellite instability (MSI) status may affect the efficacy of adjuvant chemotherapy in gastric cancer. In this study, the clinical characteristics of MSI-high (MSI-H) gastric cancer and the predictive value of... -
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- β1,4-Galactosyltransferase V Modulates Breast Cancer Stem Cells through Wnt/β-catenin Signaling Pathway
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Tang W, Li M, Qi X, Li J
- KMID: 2507935
- Cancer Res Treat.
- 2020 Oct;52(4):1084-1102.
- doi: 10.4143/crt.2020.093
Purpose Breast cancer stem cells (BCSCs) contribute to the initiation, development, and recurrence of breast carcinomas. β1,4-Galactosyltransferase V (B4GalT5), which catalyzes the addition of galactose to GlcNAcβ1-4Man of N-glycans, is involved... -
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- Evaluation of Circulating Tumor DNA in Patients with Ovarian Cancer Harboring Somatic PIK3CA or KRAS Mutations
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Ogasawara A, Hihara T, Shintani D, Yabuno A, Ikeda Y, Tai K, Fujiwara K, Watanabe K, Hasegawa K
- KMID: 2507947
- Cancer Res Treat.
- 2020 Oct;52(4):1219-1228.
- doi: 10.4143/crt.2019.688
Purpose Circulating tumor DNA (ctDNA) is an attractive source for liquid biopsy to understand molecular phenotypes of a tumor non-invasively, which is also expected to be both a diagnostic and prognostic... -
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- Seminal Vesicle Involvement by Carcinoma In Situ of the Bladder: Clonal Analysis Using Next-Generation Sequencing to Elucidate the Mechanism of Tumor Spread
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Park HS, Shin HB, Lee MS, Kim JH, Kim SY, Park J
- KMID: 2507953
- Cancer Res Treat.
- 2020 Oct;52(4):1283-1287.
- doi: 10.4143/crt.2020.002
We present a rare case of urothelial carcinoma in situ (CIS), which invades the prostate and seminal vesicle (SV). A 70-year-old man underwent transurethral resection of bladder (TURB), and the... -
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- FGFR4 Gly388Arg Polymorphism Affects the Progression of Gastric Cancer by Activating STAT3 Pathway to Induce Epithelial to Mesenchymal Transition
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Ye Y, Li J, Jiang D, Li J, Xiao C, Li Y, Han C, Zhao C
- KMID: 2507942
- Cancer Res Treat.
- 2020 Oct;52(4):1162-1177.
- doi: 10.4143/crt.2020.138
Purpose Fibroblast growth factor receptor 4 (FGFR4) plays a critical role in cancer progression involving in tumor proliferation, invasion, and metastasis. This study clarified the role of FGFR4-Arg388 variant in gastric... -
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- Evaluation of the American Joint Committee on Cancer (AJCC) 8th Edition Staging System for Hepatocellular Carcinoma in 1,008 Patients with Curative Resection
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Park S, Choi S, Cho YA, Sinn DH, Kim JM, Park CK, Ha SY
- KMID: 2507940
- Cancer Res Treat.
- 2020 Oct;52(4):1145-1152.
- doi: 10.4143/crt.2020.208
Purpose Recently, the 8th edition staging system of the American Joint Committee on Cancer (AJCC) for hepatocellular carcinoma (HCC) was released, including a change in T category. We aimed to validate... -
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- Nomogram for Predicting Central Lymph Node Metastasis in Papillary Thyroid Cancer: A Retrospective Cohort Study of Two Clinical Centers
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Yang Z, Heng Y, Lin J, Lu C, Yu D, Tao L, Cai W
- KMID: 2507928
- Cancer Res Treat.
- 2020 Oct;52(4):1010-1018.
- doi: 10.4143/crt.2020.254
Purpose Central lymph node metastasis (CNM) are highly prevalent but hard to detect preoperatively in papillary thyroid carcinoma (PTC) patients, while the significance of prophylactic compartment central lymph node dissection (CLND)... -
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- Early Assessment of Response to Neoadjuvant Chemotherapy with 18F-FDG-PET/CT in Patients with Advanced-Stage Ovarian Cancer
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Chung YS, Kim HS, Lee JY, Kang WJ, Nam EJ, Kim S, Kim SW, Kim YT
- KMID: 2507946
- Cancer Res Treat.
- 2020 Oct;52(4):1211-1218.
- doi: 10.4143/crt.2019.506
Purpose The aim of this study was to evaluate the ability of sequential 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) after one cycle of neoadjuvant chemotherapy (NAC) to predict chemotherapy response before... -
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- Real-World Data of Pyrotinib-Based Therapy in Metastatic HER2-Positive Breast Cancer: Promising Efficacy in Lapatinib-Treated Patients and in Brain Metastasis
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Lin Y, Lin M, Zhang J, Wang B, Tao Z, Du Y, Zhang S, Cao J, Wang L, Hu X
- KMID: 2507933
- Cancer Res Treat.
- 2020 Oct;52(4):1059-1066.
- doi: 10.4143/crt.2019.633
Purpose Pyrotinib is a newly-developed irreversible pan-ErbB receptor tyrosine kinase inhibitor. This study reported the first real-world data of pyrotinib-based therapy in metastatic human epidermal growth factor receptor 2 (HER2)-positive breast... -
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- Protective Effects of N-Acetylcysteine against Radiation-Induced Oral Mucositis In Vitro and In Vivo
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Kim HJ, Kang SU, Lee YS, Jang JY, Kang H, Kim CH
- KMID: 2507929
- Cancer Res Treat.
- 2020 Oct;52(4):1019-1030.
- doi: 10.4143/crt.2020.012
Purpose Radiation-induced oral mucositis limits delivery of high-dose radiation to targeted cancers. Therefore, it is necessary to develop a treatment strategy to alleviate radiation-induced oral mucositis during radiation therapy. We... -
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