- Laminin Modulates the Stem Cell Population in LM05-E Murine Breast Cancer Cells through the Activation of the MAPK/ERK Pathway
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Berardi DE, Raffo D, Todaro LB, Simian M
- KMID: 2394806
- Cancer Res Treat.
- 2017 Oct;49(4):869-879.
- doi: 10.4143/crt.2016.378
PURPOSE: We investigated the effects of laminin on the fraction of cells with self-renewing capacity in the estrogen-dependent, tamoxifen-sensitive LM05-E breast cancer cell line. We also determined whether laminin affected... -
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- Survival of Cancer Patients in Northeast China: Analysis of Sampled Cancers from Population-Based Cancer Registries
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Li Y, Yu L, Na J, Li S, Liu L, Mu H, Bi X, An X, Li X, Dong W, Pan G
- KMID: 2394829
- Cancer Res Treat.
- 2017 Oct;49(4):1106-1113.
- doi: 10.4143/crt.2016.613
PURPOSE: The cancer survival was characterized by following up sampled subgroups of cancer cases from three population-based cancer registries in Northeast China. MATERIALS AND METHODS: Survival analysis was used to analyze... -
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- Induction Chemotherapy with Gemcitabine and Cisplatin Followed by Simultaneous Integrated Boost–Intensity Modulated Radiotherapy with Concurrent Gemcitabine for Locally Advanced Unresectable Pancreatic Cancer: Results from a Feasibility Study
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Woo SM, Kim MK, Joo J, Yoon KA, Park B, Park SJ, Han SS, Lee JH, Hong EK, Kim YH, Moon H, Kong SY, Kim TH, Lee WJ
- KMID: 2394821
- Cancer Res Treat.
- 2017 Oct;49(4):1022-1032.
- doi: 10.4143/crt.2016.495
PURPOSE: This study assessed the feasibility and compliance of induction chemotherapy with gemcitabine and cisplatin followed by simultaneous integrated boost–intensity modulated radiotherapy (SIB-IMRT) with concurrent gemcitabine in patients with locally... -
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- Identification of Diverse Adenosine-to-Inosine RNA Editing Subtypes in Colorectal Cancer
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Lee SH, Kim HP, Kang JK, Song SH, Han SW, Kim TY
- KMID: 2394826
- Cancer Res Treat.
- 2017 Oct;49(4):1077-1087.
- doi: 10.4143/crt.2016.301
PURPOSE: RNA editing generates protein diversity by altering RNA sequences in coding regions without changing the overall DNA sequence. Adenosine-to-inosine (A-to-I) RNA editing events have recently been reported in some... -
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- Randomized Phase II Study of Afatinib Plus Simvastatin Versus Afatinib Alone in Previously Treated Patients with Advanced Nonadenocarcinomatous Non-small Cell Lung Cancer
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Lee Y, Lee KH, Lee GK, Lee SH, Lim KY, Joo J, Go YJ, Lee JS, Han JY
- KMID: 2394819
- Cancer Res Treat.
- 2017 Oct;49(4):1001-1011.
- doi: 10.4143/crt.2016.546
PURPOSE: This phase II study examined whether the addition of simvastatin to afatinib provides a clinical benefit compared with afatinib monotherapy in previously treated patients with nonadenocarcinomatous non-small cell lung... -
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- Risk Factors of Female Breast Cancer in Vietnam: A Case-Control Study
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Trieu PD, Mello-Thoms C, Peat JK, Do TD, Brennan PC
- KMID: 2394818
- Cancer Res Treat.
- 2017 Oct;49(4):990-1000.
- doi: 10.4143/crt.2016.488
PURPOSE: Rates of women with breast cancer have increased rapidly in recent years in Vietnam, with over 10,000 new patients contracting the disease every year. This study was conducted to... -
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- Effects of Soy Product Intake and Interleukin Genetic Polymorphisms on Early Gastric Cancer Risk in Korea: A Case-Control Study
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Yang S, Park Y, Lee J, Choi IJ, Kim YW, Ryu KW, Sung J, Kim J
- KMID: 2394823
- Cancer Res Treat.
- 2017 Oct;49(4):1044-1056.
- doi: 10.4143/crt.2016.515
PURPOSE: The current study investigated whether the combined effects of soy intake and genetic polymorphisms of interleukin (IL) genes modify gastric cancer risk. MATERIALS AND METHODS: A total of 377 cases... -
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- Prognostic Factors and Scoring Model for Survival in Metastatic Biliary Tract Cancer
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Park HS, Park JS, Chun YJ, Roh YH, Moon J, Chon HJ, Choi HJ, Park JS, Lee DK, Lee SJ, Yoon DS, Jeung HC
- KMID: 2394831
- Cancer Res Treat.
- 2017 Oct;49(4):1127-1139.
- doi: 10.4143/crt.2016.538
PURPOSE: Metastatic biliary tract cancer (mBTC) has a dismal prognosis. In this study, an independent dataset of patients with mBTC was used to implement and validate a routine clinico-laboratory parameter-based... -
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- Gonadal and Sexual Dysfunction in Childhood Cancer Survivors
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Yoon JY, Park HJ, Ju HY, Yoon JH, Chung JS, Hwang SH, Lee DO, Shim HY, Park BK
- KMID: 2394824
- Cancer Res Treat.
- 2017 Oct;49(4):1057-1064.
- doi: 10.4143/crt.2016.197
PURPOSE: Few studies have addressed gonadal and sexual dysfunctions in childhood cancer survivors. We evaluated the prevalence rates and risk factors for gonadal failure among adolescent/young adult childhood cancer survivors... -
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- Incorporating Erlotinib or Irinotecan Plus Cisplatin into Chemoradiotherapy for Stage III Non-small Cell Lung Cancer According to EGFR Mutation Status
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Lee Y, Han JY, Moon SH, Nam BH, Lim KY, Lee GK, Kim HT, Yun T, An HJ, Lee JS
- KMID: 2394817
- Cancer Res Treat.
- 2017 Oct;49(4):981-989.
- doi: 10.4143/crt.2016.522
PURPOSE: Concurrent chemoradiotherapy (CCRT) is the standard care for stage III non-small cell lung cancer (NSCLC) patients; however, a more effective regimen is needed to improve the outcome by better... -
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- Effect of Adjuvant Chemotherapy after Complete Resection for Pathologic Stage IB Lung Adenocarcinoma in High-Risk Patients as Defined by a New Recurrence Risk Scoring Model
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Jang HJ, Cho S, Kim K, Jheon S, Yang HC, Kim DK
- KMID: 2394809
- Cancer Res Treat.
- 2017 Oct;49(4):898-905.
- doi: 10.4143/crt.2016.312
PURPOSE: We conducted a retrospective analysis to determine if adjuvant chemotherapy prolongs overall survival in patients with pathologic stage IB lung adenocarcinoma who had undergone complete resection and were defined... -
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- Neurocognitive and Psychological Functioning of Children with an Intracranial Germ Cell Tumor
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Park Y, Yu ES, Ha B, Park HJ, Kim JH, Kim JY
- KMID: 2394815
- Cancer Res Treat.
- 2017 Oct;49(4):960-969.
- doi: 10.4143/crt.2016.204
PURPOSE: This study was conducted to investigate the neurocognitive functioning of children with intracranial germ cell tumor (IGCT) prior to receiving proton beam therapy (PBT), and to identify differential characteristics... -
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- Anti-angiogenic Therapy in Patients with Advanced Gastric and Gastroesophageal Junction Cancer: A Systematic Review
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Chen LT, Oh DY, Ryu MH, Yeh KH, Yeo W, Carlesi R, Cheng R, Kim J, Orlando M, Kang YK
- KMID: 2394805
- Cancer Res Treat.
- 2017 Oct;49(4):851-868.
- doi: 10.4143/crt.2016.176
Despite advancements in therapy for advanced gastric and gastroesophageal junction cancers, their prognosis remains dismal. Tumor angiogenesis plays a key role in cancer growth and metastasis, and recent studies indicate... -
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- Korean Cancer Patients' Awareness of Clinical Trials, Perceptions on the Benefit and Willingness to Participate
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Lim Y, Lim JM, Jeong WJ, Lee KH, Keam B, Kim TY, Kim TM, Han SW, Oh DY, Kim DW, Kim TY, Heo DS, Bang YJ, Im SA
- KMID: 2394822
- Cancer Res Treat.
- 2017 Oct;49(4):1033-1043.
- doi: 10.4143/crt.2016.413
PURPOSE: The purpose of this study was to assess current levels of awareness of clinical trials (CTs), perceptions regarding their benefits and willingness to participate to CTs among Korean cancer... -
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- The Prognostic Values of Preoperative Tumor Volume and Tumor Diameter in T1N0 Papillary Thyroid Cancer
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Lim ST, Jeon YW, Suh YJ
- KMID: 2394808
- Cancer Res Treat.
- 2017 Oct;49(4):890-897.
- doi: 10.4143/crt.2016.325
PURPOSE: The current TNM staging system for papillary thyroid cancer (PTC), which is based on tumor diameter, may not precisely reflect the true tumor burden. Therefore, we investigated whether preoperative... -
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- Patient-Derived Xenograft Models of Epithelial Ovarian Cancer for Preclinical Studies
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Heo EJ, Cho YJ, Cho WC, Hong JE, Jeon HK, Oh DY, Choi YL, Song SY, Choi JJ, Bae DS, Lee YY, Choi CH, Kim TJ, Park WY, Kim BG, Lee JW
- KMID: 2394811
- Cancer Res Treat.
- 2017 Oct;49(4):915-926.
- doi: 10.4143/crt.2016.322
PURPOSE: Patient-derived tumor xenografts (PDXs) can provide more reliable information about tumor biology than cell line models. We developed PDXs for epithelial ovarian cancer (EOC) that have histopathologic and genetic... -
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- Identification of a Novel BRCA1 Pathogenic Mutation in Korean Patients Following Reclassification of BRCA1 and BRCA2 Variants According to the ACMG Standards and Guidelines Using Relevant Ethnic Controls
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Park JS, Nam EJ, Park HS, Han JW, Lee JY, Kim J, Kim TI, Lee ST
- KMID: 2394820
- Cancer Res Treat.
- 2017 Oct;49(4):1012-1021.
- doi: 10.4143/crt.2016.433
PURPOSE: Comparison of variant frequencies in the general population has become an essential part of the American College of Medical Genetics and Genomics (ACMG) standards and guidelines for interpreting sequence... -
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- Education Level Is a Strong Prognosticator in the Subgroup Aged More Than 50 Years Regardless of the Molecular Subtype of Breast Cancer: A Study Based on the Nationwide Korean Breast Cancer Registry Database
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Hwang KT, Noh W, Cho SH, Yu J, Park MH, Jeong J, Lee HJ, Kim J, Oh S, Kim YA, Korean Breast Cancer Society
- KMID: 2394830
- Cancer Res Treat.
- 2017 Oct;49(4):1114-1126.
- doi: 10.4143/crt.2016.528
PURPOSE: This study investigated the role of the education level (EL) as a prognostic factor for breast cancer and analyzed the relationship between the EL and various confounding factors. MATERIALS AND... -
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- Practice Patterns Regarding Multidisciplinary Cancer Management and Suggestions for Further Refinement: Results from a National Survey in Korea
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Lee YG, Oh S, Kimm H, Koo DH, Kim DY, Kim BS, Lee SS
- KMID: 2394834
- Cancer Res Treat.
- 2017 Oct;49(4):1164-1169.
- doi: 10.4143/crt.2016.517
PURPOSE: This study was conducted to explore the process and operation of a cancer multidisciplinary team (MDT) after the reimbursement decision in Korea, and to identify ways to overcome the... -
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- Prognostic Impact of Elective Supraclavicular Nodal Irradiation for Patients with N1 Breast Cancer after Lumpectomy and Anthracycline Plus Taxane-Based Chemotherapy (KROG 1418): A Multicenter Case-Controlled Study
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Kim H, Park W, Yu JI, Choi DH, Huh SJ, Kim YJ, Lee ES, Lee KS, Kang HS, Park IH, Shin KH, Wee CW, Kim K, Park KR, Kim YB, Ahn SJ, Lee JH, Kim JH, Chun M, Lee HS, Kim JS, Cha J
- KMID: 2394816
- Cancer Res Treat.
- 2017 Oct;49(4):970-980.
- doi: 10.4143/crt.2016.382
PURPOSE: This study was conducted to evaluate the impact of supraclavicular lymph node radiotherapy (SCNRT) on N1 breast cancer patients receiving post-lumpectomy whole-breast irradiation (WBI) and anthracycline plus taxane-based (AT)... -
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