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The Effects of Meal Timing and Frequency, Caloric Restriction, and Fasting on Cardiovascular Health: an Overview

Maugeri A, Vinciguerra M

Cardiovascular disease (CVD), which is the leading cause of death worldwide, is strongly affected by diet. Diet can affect CVD directly by modulating the composition of vascular plaques, and indirectly...
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Effects of Low-Calorie Diet Including High Protein-Low Carbohydrate Protein Bar on Weight Loss and Serum Lipid Indicators in Overweight Women according to Dietary Compliance

Park D, Lee HJ, Son SM

OBJECTIVES: This study was conducted to investigate the effect of a 6-week low-calorie diet (LCD) program including high protein-low carbohydrate protein bar on weight loss, blood pressure, and blood lipid...
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Effects of caloric restriction on the expression of lipocalin-2 and its receptor in the brown adipose tissue of high-fat diet-fed mice

Park KA, Jin Z, An HS, Lee JY, Jeong EA, Choi EB, Kim KE, Shin HJ, Lee JE, Roh GS

Obesity causes inflammation and impairs thermogenic functions in brown adipose tissue (BAT). The adipokine lipocalin 2 (LCN2) has been implicated in inflammation and obesity. Herein, we investigated the protective effects...
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What Is the Role of Resistance Exercise in Improving the Cardiometabolic Health of Adolescents with Obesity?

Lee S, Kim Y, Kuk JL

Traditionally, individuals with obesity have been encouraged to participate in aerobic exercise for long-term weight management and improved obesity-related health outcomes. Recently, resistance exercise has become a popular mode of...
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Gastric Ulceration and Bleeding with Hemodynamic Instability Caused by an Intragastric Balloon for Weight Loss

Reed L, Edriss H, Nugent K

Obesity in the United States is a medical crisis with many people attempting to lose weight with caloric restriction. Some patients choose minimally invasive weight loss solutions, such as intragastric...
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Preoperative Nutritional Management of Patients with Morbid Obesity

Hong J, Park S

Since patients with morbid obesity undergoing bariatric surgery are vulnerable to micronutrient deficiencies, close monitoring and supplementation are necessary. The importance of screening prior to surgery has increased in recent...
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A Multi-stage Carcinogenesis Model to Investigate Caloric Restriction as a Potential Tool for Post-irradiation Mitigation of Cancer Risk

Tani S, Blyth BJ, Shang Y, Morioka T, Kakinuma S, Shimada Y

The risk of radiation-induced cancer adds to anxiety in low-dose exposed populations. Safe and effective lifestyle changes which can help mitigate excess cancer risk might provide exposed individuals the opportunity...
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Six-week Diet Correction for Body Weight Reduction and Its Subsequent Changes of Gut Microbiota: A Case Report

Oh B, Kim JS, Kweon M, Kim BS, Huh IS

Impact of intestinal microbes on obesity and health is a new topic recently started to get attention. Comparing to the global concern and research trends, there are few research on...
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Autophagy: A Novel Therapeutic Target for Diabetic Nephropathy

Kume S, Koya D

Diabetic nephropathy is a leading cause of end stage renal disease and its occurance is increasing worldwide. The most effective treatment strategy for the condition is intensive treatment to strictly...
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Perspective of Small-Molecule AdipoR Agonist for Type 2 Diabetes and Short Life in Obesity

Okada-Iwabu M, Iwabu M, Ueki K, Yamauchi T, Kadowaki T

Obesity associated with unhealthy diet and lack of exercise is shown to contribute to the onset and/or aggravation of the metabolic syndrome and diabetes, thus placing affected individuals at increased...
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How Leptin Controls the Drive to Eat

Patterson , Myers MG

  • KMID: 2271158
  • Korean J Obes.
  • 2015 Jun;24(2):69-77.
A complex set of brain based systems modulate feeding to maintain constant body weight. The adipose derived-hormone, leptin, plays a crucial role in this control by acting on diverse leptin...
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Decreased Intermuscular Adipose Tissue due to Caloric Restriction in Obese Korean Women

Park JS, Lee HO, Kim YS, Yim JE

BACKGROUND: This study investigated the effects of caloric restriction on thigh intermuscular adipose tissue (IMAT) and the associations of IMAT and metabolic risk factors. METHODS: Thirty-three obese Korean women (BMI 27.2+/-2.5...
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Molecular Links between Caloric Restriction and Sir2/SIRT1 Activation

Wang Y

Ageing is the most significant risk factor for a range of prevalent diseases, including cancer, cardiovascular disease, and diabetes. Accordingly, interventions are needed for delaying or preventing disorders associated with...
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Moderate diet-induced weight loss is associated with improved insulin sensitivity in middle-aged healthy obese Korean women

Lee HO, Yim JE, Kim YS, Choue R

  • KMID: 2313766
  • Nutr Res Pract.
  • 2014 Aug;8(4):469-475.
BACKGROUND/OBJECTIVE: The goal of the present study was to investigate the effects of moderate caloric restriction on beta-cell function and insulin sensitivity in middle-aged obese Korean women. SUBJECTS/METHODS: Fifty-seven obese pre-menopausal...
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Nonalcoholic Fatty Liver Disease: Lifestyle Modification

Yoo KD, Jun DW

  • KMID: 2128460
  • Korean J Med.
  • 2014 Apr;86(4):416-424.
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease. The prevalence of NAFLD is growing gradually worldwide with increases in obesity, sedentary lifestyles, and an...
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Short-Term Caloric Restriction Does Not Reduce Bone Mineral Density in Rats with Early Type 2 Diabetes

Jeon YK, Kim WJ, Shin MJ, Chung HY, Kim SS, Kim BH, Kim SJ, Kim YK, Kim IJ

BACKGROUND: The effect of caloric restriction (CR) in the setting of diabetes on bone metabolism has not yet been fully studied. The aim of this study is to determine if...
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Intermittent Fasting in Diabetic Patients

Cho DH

Obesity is becoming increasingly prevalent worldwide. It is linked to health problems including cardiovascular disease, diabetes, cancer, musculoskeletal problems and even psychiatric problems. Intermittent fasting is an interventional strategy wherein...
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Effects of age on changes of body composition through caloric restriction in overweight and obese women

Yim JE, Kim YS, Choue R

  • KMID: 2327121
  • J Nutr Health.
  • 2013 Oct;46(5):410-417.
Caloric restriction is recognized as one of the best treatment options for obesity, and is associated with changes in body composition. The purpose of this study was to determine the...
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The Interplay between Autophagy and Aging

Pyo JO, Yoo SM, Jung YK

Numerous studies have established a link between autophagy and aging; however, the relationship has not been clearly defined. Aging is a very complex process caused by the accumulation of various...
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SIRT1 in Type 2 Diabetes: Mechanisms and Therapeutic Potential

Kitada M, Koya D

The prevalence of type 2 diabetes mellitus (T2DM) has been increasing worldwide. Therefore, a novel therapeutic strategy by which to prevent T2DM is urgently required. Calorie restriction (CR) can retard...
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