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MRP8 promotes Th17 differentiation via upregulation of IL-6 production by fibroblast-like synoviocytes in rheumatoid arthritis

Lee DG, Woo JW, Kwok SK, Cho ML, Park SH

  • KMID: 2154239
  • Exp Mol Med.
  • 2013 Apr;45(4):e20.
Myeloid-related protein (MRP)8/MRP14 is an endogenous Toll-like receptor 4 (TLR4) ligand and is abundant in synovial fluid (SF) of rheumatoid arthritis (RA) patients. Belonging to damage-associated molecular patterns, it amplifies...
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