- T-Type Calcium Channels Are Required to Maintain Viability of Neural Progenitor Cells
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Kim JW, Oh HA, Lee SH, Kim KC, Eun PH, Ko MJ, Gonzales E, Seung H, Kim S, Bahn GH, Shin CY
- KMID: 2421721
- Biomol Ther.
- 2018 Sep;26(5):439-445.
- doi: 10.4062/biomolther.2017.223
T-type calcium channels are low voltage-activated calcium channels that evoke small and transient calcium currents. Recently, T-type calcium channels have been implicated in neurodevelopmental disorders such as autism spectrum disorder... -
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- Intracisternal Administration of Voltage Dependent Calcium Channel Blockers Attenuates Orofacial Inflammatory Nociceptive Behavior in Rats
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Won KA, Park SH, Kim BK, Baek KS, Yoon DH, Ahn DK
- KMID: 2170724
- Int J Oral Biol.
- 2011 Jun;36(2):43-50.
Voltage dependent calcium channel (VDCC), one of the most important regulator of Ca2+ concentration in neuron, play an essential role in the central processing of nociceptive information. The present study... -
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- The Role of Calcium Affecting Signal Pathway Related to Nitric Oxide-induced Cytotoxicity in H9c2 Cardiac Myoblast
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Lee BH, Jung KM, Ahn BK, Mun YJ, Oh JM, Kim JJ, Choi MK, Park ST, Chung YT
- KMID: 2224547
- Korean J Anat.
- 2000 Oct;33(5):587-594.
Nitric oxide (NO) elevates intracellular calcium. But the actions of calcium in NO-induced cell death are not well understood. This study was carried out to investigate the signal transduction pathways... -
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- Observation of the Incidence of Acrosome Reaction in Human Spermatozoa Treated with Mibefradil as a T-type Ca2+i Channels Inhibitor
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Lee JH, Lee IS, Kim YC, Son WY, Lee JH, Han CT
- KMID: 2235708
- Korean J Fertil Steril.
- 2000 Mar;27(1):9-14.
OBJECTIVE : The sperm acrosome reaction is a Ca2+ -dependent exocytotic event that is triggered by adhesion to the mammalian egg's zona pellucida. Previous studies suggested a role of Ca2+... -
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- Mechanisms of Antiepileptic Drugs
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Kim JM
- KMID: 1816473
- J Korean Epilepsy Soc.
- 2000 Dec;4(2):108-118.
Established antiepileptic drugs (AEDs) decrease membrane excitability by interacting with neurotransmitter receptors or ion channels. AEDs developed prior to 1980 appear to act on sodium channels, gamma-amino butyric acid type... -
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- Effect of an L- and T-Type Calcium Channel Blocker on 24-Hour Systolic Blood Pressure and Heart Rate in Hypertensive Patients
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Komukai M, Tsutsumi T, Ebado M, Takeyama Y
- KMID: 2225015
- Korean Circ J.
- 2012 Apr;42(4):231-238.
- doi: 10.4070/kcj.2012.42.4.231
BACKGROUND AND OBJECTIVES: The aim of this study was to evaluate the effects of an L- and T-type calcium channel blocker (CCB) on 24-hour systolic blood pressure (24-hour SBP) and... -
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- A Computational Modeling Reveals That Strength of Inhibitory Input, E/I Balance, and Distance of Excitatory Input Modulate Thalamocortical Bursting Properties
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Park S, Sohn JW, Cho J, Huh Y
- KMID: 2463712
- Exp Neurobiol.
- 2019 Oct;28(5):568-577.
- doi: 10.5607/en.2019.28.5.568
The thalamus is a brain structure known to modulate sensory information before relaying to the cortex. The unique ability of a thalamocortical (TC) neuron to switch between the high frequency... -
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