- Sox-4 is a positive regulator of Hep3B and HepG2 cells' apoptosis induced by prostaglandin (PG)A2 and 12-PGJ2.
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Ahn SG, Kim HS, Jeong SW, Kim BE, Rhim HS, Shim JY, Kim JW, Lee JH, Kim IK
- KMID: 1380233
- Exp Mol Med.
- 2002 Jul;34(3):243-249.
We reported earlier that expression of Sox-4 was found to be elevated during prostaglandin (PG) A2 and delta(12)-PGJ(12) induced apoptosis in human hepatocarcinoma Hep3B cells. In this study, the role... -
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- Comparison of basophil histamine releasability between atopic and nonatopic thmatics
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Son JW, Kim YK, Chung JW, Lee SR, Cho SH, Min KU, Koh YY, Kim YY
- KMID: 648073
- J Korean Med Sci.
- 1999 Apr;14(2):153-158.
- doi: 10.3346/jkms.1999.14.2.153
To compare the mediator releasability between atopic and nonatopic asthmatics, we measured basophil histamine releasability (BaHR) using a calcium-ionophore A23187 and anti-IgE in 137 subjects who were treated at Seoul... -
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- Calcium-influx increases SOD1 aggregates via nitric oxide in cultured motor neurons
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Kim HJ, Im W, Kim S, Kim SH, Sung JJ, Kim M, Lee KW
- KMID: 1090960
- Exp Mol Med.
- 2007 Oct;39(5):574-582.
Familial amyotrophic lateral sclerosis (fALS) is caused by mutations in Cu/Zn-superoxide dismutase (SOD1), and SOD1 aggregation and calcium toxicity are involved in neuronal death. However, the effect of altered calcium... -
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- Transglutaminase 2 inhibits apoptosis induced by calciumoverload through down-regulation of Bax
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Cho SY, Lee JH, Bae HD, Jeong EM, Jang GY, Kim CW, Shin DM, Jeon JH, Kim IG
- KMID: 983956
- Exp Mol Med.
- 2010 Sep;42(9):639-650.
- doi: 10.3858/emm.2010.42.9.063
An abrupt increase of intracellular Ca2+ is observed in cells under hypoxic or oxidatively stressed conditions. The dysregulated increase of cytosolic Ca2+ triggers apoptotic cell death through mitochondrial swelling and... -
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