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Relationship between Expression of Thy- midylate Synthase mRNA and Resistance of Colon and Gastric Cancer Cells to 5-FU

Cho SH, Min YD, Lee TB, Choi SM, Byun IG, Choi CH, Kim KJ

  • KMID: 2334297
  • J Korean Soc Coloproctol.
  • 2003 Apr;19(2):67-73.
PURPOSE: Thymidylate synthase (TS) is an important target for chemotherapeutic drugs such as 5-fluorouracil (5-FU). Overexpression of TS has been linked to chemotherapy resistance, but their relationship was not completely...
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