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Novel biological strategies to enhance the radiation therapeutic ratio

Kim JH, Jenrow KA, Brown SL

Successful anticancer strategies require a differential response between tumor and normal tissue (i.e., a therapeutic ratio). In fact, improving the effectiveness of a cancer therapeutic is of no clinical value...
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Mechanisms of radiation-induced normal tissue toxicity and implications for future clinical trials

Kim JH, Jenrow KA, Brown SL

To summarize current knowledge regarding mechanisms of radiation-induced normal tissue injury and medical countermeasures available to reduce its severity. Advances in radiation delivery using megavoltage and intensity-modulated radiation therapy have...
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