- The first documentation of Li-Fraumeni syndrome in Korea
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Bang YJ, Kang SH, Kim TY, Jung CW, Oh SM, Choe KJ, Kim NK
- KMID: 1054346
- J Korean Med Sci.
- 1995 Jun;10(3):205-210.
- doi: 10.3346/jkms.1995.10.3.205
Li-Fraumeni syndrome(LFS) is an autosomal dominant disorder that predisposes individuals to multiple forms of cancer including breast cancer, soft tissue sarcoma, brain tumor, osteosarcoma, leukemia, and adrenocortical carcinoma. Recently, germ-line... -
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- The mitogen-activated protein kinase phosphatase-1 (MKP-1) gene is a potential methylation biomarker for malignancy of breast cancer
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Chen FM, Chang HW, Yang SF, Huang YF, Nien PY, Yeh YT, Hou MF
- KMID: 1383797
- Exp Mol Med.
- 2012 May;44(5):356-362.
The mitogen-activated protein kinase (MAPK) phosphatase-1 (MKP-1) belongs to the MAPK cascades which are central to cell proliferation and apoptosis. The carcinogenic role of MKP-1 has been reported in many... -
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