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Effect of hypocapnia on extracellular glutamate and glycine concentrations during peri-ischemic period in the rabbit hippocampus

Choi KT, Chung JK, Kwak CS, Kim HK

Glutamate (GLU) is a neurotransmitter. Massive release of GLU and glycine (GLY) into the brain's extracellular space may be triggered by ischemia, and may result in acute neuronal lysis or...
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Immunohistochemical expression of phospholipase C in global and focal ischemic encephalopathy in gerbil: relationship with morphological changes

Koo H

Phospholipase C (PLC) and related enzymes in signal transduction system are closely linked to cellular damage in ischemic encephalopathy. This study was undertaken to elucidate the time sequential changes of...
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Protective effects of transduced Tat-DJ-1 protein against oxidative stress and ischemic brain injury

Jeong HJ, Kim DW, Kim MJ, Woo SJ, Kim HR, Kim SM, Jo HS, Hwang HS, Kim DS, Cho SW, Won MH, Han KH, Park J, Eum WS, Choi SY

  • KMID: 1506222
  • Exp Mol Med.
  • 2012 Oct;44(10):586-593.
Reactive oxygen species (ROS) contribute to the development of a number of neuronal diseases including ischemia. DJ-1, also known to PARK7, plays an important role in transcriptional regulation, acting as...
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Surface Expression of P-selectin on Platelets Is Related with Clinical Worsening in Acute Ischemic Stroke

Cha JK, Jeong MH, Kim EK, Lim YJ, Ha BR, Kim SH, Kim JW

Platelet activation has a critical role in arterial disorders. In this study, we showed that the upregulation of P-selectin expression on platelets was related with clinical worsening in acute...
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