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Region-Specific Differences in the Apoe4-dependent Response to Focal Brain Injury

Lee SE, Yang H, Sung Y, Kim Y, Park SA

  • KMID: 2519890
  • Exp Neurobiol.
  • 2021 Aug;30(4):285-293.
  • doi: 10.5607/en21022
Apolipoprotein E (apoE) plays a role in various physiological functions including lipid transport, synaptic plasticity, and immune modulation. Epidemiological studies suggest that the apoE4 allele increases the risk of post-traumatic sequelae....
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Traumatic brain injury in patients aged ≥65 years versus patients aged ≥80 years: a multicenter prospective study of mortality and medical resource utilization

Bae S, Song SW, Kim WJ, Kang Y, Kang KW, Park CB, Kang JH, Bu JH, Lee SK, Ko SY

Objective This study aimed to determine whether there is a difference in mortality and medical resource utilization between geriatric (aged ≥65 years) and super-geriatric patients (aged ≥80 years) with traumatic...
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Effects of Concurrent Tasks on Gait Performance in Children With Traumatic Brain Injury Versus Children With Typical Development

Rahman RAA, Hanapiah FA, Nikmat AW, Ismail NA, Manaf H

Objective To investigate how gait parameters in children with traumatic brain injury (TBI) versus typically developing (TD) children are influenced by secondary concurrent tasks and examine the correlations between gait...
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Treatment of patients with severe traumatic brain injury: a 7-year single institution experience

Marini CP, Petrone P, McNelis J, Lewis E, Liveris A, Stiefel MF

Background: This study was designed to compare the efficacy of multimodality monitoring and goal-directed therapy protocol (MM&GDTP), in patients with Glasgow Coma Scale (GCS) scores ≤8 with the conventional intracranial...
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Continuous heart rate variability and electroencephalography monitoring in severe acute brain injury: a preliminary study

Lee H, Jeon SB, Lee KS

Background: Decreases in heart rate variability have been shown to be associated with poor outcomes in severe acute brain injury. However, it is unknown whether the changes in heart rate...
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Brachial Plexus Injuries in Adults with Traumatic Brain Injury : A Retrospective Study

Tezel N, Can A, Cankurtaran D, Akyüz E, Çakcı A

Objective : We aimed to investigate the presence of brachial plexus injury (BPI) in traumatic brain injury (TBI) patients and to draw attention to BPI, which can be overlooked by...
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Missed Skeletal Trauma Detected by Whole Body Bone Scan in Patients with Traumatic Brain Injury

Seo Y, Whang K, Pyen J, Choi J, Kim J, Oh J

Objective : Unclear mental state is one of the major factors contributing to diagnostic failure of occult skeletal trauma in patients with traumatic brain injury (TBI). The aim of this...
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Single-Stage Reconstruction with Titanium Mesh for Compound Comminuted Depressed Skull Fracture

Eom KS

Objective : Traditionally, staged surgery has been preferred in the treatment of compound comminuted depressed fracture (FCCD) after traumatic brain injury (TBI) and involves the removal of primarily damaged bone...
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Comparative and retrospective evaluation of the predictive performance of optic nerve sheath thickness and optic nerve sheath diameter for traumatic brain injury using facial computed tomography

Sim WS, Lee SH, Yun SJ, Ryu S, Choi SW, Kim HJ, Kang TK, Oh SC, Cho SJ

Objective To evaluate the predictive performance of optic nerve sheath thickness (ONST) on the outcomes of traumatic brain injury (TBI) and to compare the inter-observer agreement To evaluate the predictive...
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Effect of complement C1-esterase inhibitor on brain edema and inflammation after mild traumatic brain injury in an animal model

Weiss E, Dhir T, Collett A, Reola M, Kaplan M, Minimo C, Omert L, Leung P

Objective Traumatic brain injury (TBI) is characterized by damage to the blood-brain barrier, inflammation, and edema formation. In this pilot study, we aimed to investigate the effects of a complement...
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Comparison of traumatic brain injury patients with brain computed tomography in the emergency department by age group

Huh KR, Kim JY, Choi SH, Yoon YH, Park SJ, Lee ES

Objective Traumatic brain injury (TBI) is an important public health concern due to its high prevalence and mortality rate among young people. We investigated the clinical and social characteristics of...
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Targeted temperature management for postcardiac arrest syndrome

Kuroda Y, Kawakita K

Neurocritical care management to improve neurologic outcome for postcardiac arrest syndrome (PCAS) has focused considerably on targeted temperature management (TTM). TTM attenuates the destructive processes following ischemia/reperfusion in PCAS. The...
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Clinical report and literature review on patients treated with group exposure to hydrogen sulfide

Kim MS, Kang JH, Kim YW, Park CM, Park CH, Yoon YS, Ji JG

  • KMID: 2501771
  • J Korean Soc Emerg Med.
  • 2020 Feb;31(1):17-22.
Objective: This study examined the clinical manifestations, treatment, and prognostic factors of hydrogen sulfide intoxication. Methods: Twelve cases of hydrogen sulfide leaking from a wastewater treatment company in Sasang-gu, Busan were...
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Comparison of preventive effect of seat belt on traumatic brain injury by age in motor vehicle collision

Chai HS, Choe BH, Hong SJ, Kim SC, Lee HJ, Park KJ, Lee JH, Kim H, Lee SW

  • KMID: 2511357
  • J Korean Soc Emerg Med.
  • 2020 Oct;31(5):448-457.
Objective: This study examined whether the preventive effects of the safety belt on traumatic brain injury (TBI) from motor vehicle collisions (MVCs) differ according to the occupants’ age. Methods: This study...
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Differential Effects of Pentoxifylline on Learning and Memory Impairment Induced by Hypoxic-ischemic Brain Injury in Rats

Halis H, Bitiktaş , Baştuğ O, Tan B, Kavraal S, Güneş T, Süer C

OBJECTIVE: Hypoxic-ischemic (HI) brain injury in the human perinatal period often leads to significant long-term neurobehavioral dysfunction in the cognitive and sensory-motor domains. Using a neonatal HI injury model (unilateral...
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New prehospital scoring system for traumatic brain injury to predict mortality and severe disability using motor Glasgow Coma Scale, hypotension, and hypoxia: a nationwide observational study

Gang MC, Hong KJ, Shin SD, Song KJ, Ro YS, Kim TH, Park JH, Jeong J

OBJECTIVE: Assessing the severity of injury and predicting outcomes are essential in traumatic brain injury (TBI). However, the respiratory rate and Glasgow Coma Scale (GCS) of the Revised Trauma Score...
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Exploratory, cognitive, and depressive-like behaviors in adult and pediatric mice exposed to controlled cortical impact

Lee SW, Jang MS, Jeong SH, Kim H

OBJECTIVE: Sequelae of behavioral impairments associated with human traumatic brain injury (TBI) include neurobehavioral problems. We compared exploratory, cognitive, and depressive-like behaviors in pediatric and adult male mice exposed to...
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Trends in demographics and outcome of patients presenting with traumatic brain injury

Kadar R, Rochford D, Omi E, Thomas Y, Patel K, Kulstad E

OBJECTIVE: To analyze the trends in demographics and outcomes of patients presenting with traumatic brain injury by performing a retrospective database review of the Illinois Department of Public Health (IDPH)...
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Assessment and management of coagulopathy in neurocritical care

Salem AM, Roh D, Kitagawa R, Choi HA, Chang TR

Coagulopathy may be defined as the loss of balance between hemostatic and fibrinolytic processes resulting in excessive bleeding, intravascular thrombosis or abnormalities in coagulation testing. It is frequently encountered across...
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Dizziness in Traumatic Brain Injury: Visual-Vestibular Dysfunction, Neurotological Approach

Jeong SH

Traumatic brain injury (TBI) could give rise to variable clinical manifestations based on the involved structures of our bodies. Although there are no structural abnormalities proven, the patients with mild...
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