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NF-kappaB-Mediated Regulation of Osteoclastogenesis

Boyce BF, Xiu Y, Li J, Xing L, Yao Z

Osteoclasts are multinucleated cells formed mainly on bone surfaces in response to cytokines by fusion of bone marrow-derived myeloid lineage precursors that circulate in the blood. Major advances in understanding...
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Nuclear Factor-Kappa B Regulation of Osteoclastogenesis and Osteoblastogenesis

Boyce BF, Li J, Yao Z, Xing L

Maintenance of skeletal integrity requires the coordinated activity of multinucleated bone-resorbing osteoclasts and bone-forming osteoblasts. Osteoclasts form resorption lacunae on bone surfaces in response to cytokines by fusion of precursor...
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