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Radiation-induced immune responses: mechanisms and therapeutic perspectives

Jeong H, Bok S, Hong BJ, Choi HS, Ahn GO

Recent advancement in the radiotherapy technology has allowed conformal delivery of high doses of ionizing radiation precisely to the tumors while sparing large volume of the normal tissues, which have...
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Tumor hypoxia and reoxygenation: the yin and yang for radiotherapy

Hong BJ, Kim J, Jeong H, Bok S, Kim YE, Ahn GO

Tumor hypoxia, a common feature occurring in nearly all human solid tumors is a major contributing factor for failures of anticancer therapies. Because ionizing radiation depends heavily on the presence...
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The Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Pathway in Osteoblasts

Greenblatt MB, Shim JH, Bok S, Kim JM

Extracellular signal-regulated kinases (ERKs) are evolutionarily ancient signal transducers of the mitogen-activated protein kinase (MAPK) family that have long been linked to the regulation of osteoblast differentiation and bone formation....
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