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Tramadol as a Voltage-Gated Sodium Channel Blocker of Peripheral Sodium Channels Na v 1.7 and Na v 1.5

Bok CS, Kim RE, Cho YY, Choi JS

Tramadol is an opioid analog used to treat chronic and acute pain. Intradermal injections of tramadol at hundreds of millimoles have been shown to produce a local anesthetic effect. We...
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